Bile salts at the air–water interface: Adsorption and desorption

Maldonado-Valderrama, Julia; Muros-Cobos, Jesús L.; Holgado-Terriza, Juan A.; Cabrerizo-Vílchez, Miguel A.

doi:10.1016/j.colsurfb.2014.05.014

Cited by 33 publications

(40 citation statements)

References 26 publications

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“…Figures 7a and 7b also include the curves for adsorption of pure NaTDC as a reference, illustrating a sigmoidal interfacial tension isotherm and a maximum in the dilatational modulus vs bulk concentration as reported for other bile salts. 38 By comparing these reference curves with those of Pluronic/NaTDC mixture, we can elucidate the adsorption process as a function of the BS concentration. As a general trend, it can be seen that at low NaTDC concentrations there exists a strong deviation of both interfacial tension isotherms and dilatational moduli of mixed systems from pure bile salt curves, indicating that the adsorption is mainly controlled by Pluronics.…”

Section: Resultsmentioning

confidence: 99%

Interactions between Pluronics (F127 and F68) and Bile Salts (NaTDC) in the Aqueous Phase and the Interface of Oil-in-Water Emulsions

et al. 2013

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Pluronics are being introduced in food research in order to delay lipid digestion, with the length of hydrophilic and hydrophobic chains playing an important role in the rate of such a process. Since bile salts play a crucial role in the lipid digestion process, the aim of this work is to analyze the interactions between Pluronic F127 or F68 and the bile salt NaTDC when the latter is added at physiological concentrations. These interactions are studied at the Pluronic-covered oil-water interface and in the aqueous phase of Pluronic-stabilized emulsions. This work has been carried out with techniques such as differential scanning calorimetry, interfacial tension, dilatational rheology, and scanning electron microscopy. As a result, Pluronic F127 was shown to be more resistant to displacement by bile salt than F68 at the oil-water interface due to the larger steric hindrance and interfacial coverage provided. In addition, Pluronics have the ability to compete for the oil-water interface and interact in the bulk with the bile salt. Concretely, Pluronic F127 seems to interact with more molecules of bile salt in the bulk, thus hindering their adsorption onto the oil-water interface. As a conclusion, Pluronic F127 affects to a larger extent the ability of bile salt to promote the further cascade of lipolysis in the presence of lipase owing to a combination of interfacial and bulk events.

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Section: Resultsmentioning

confidence: 99%

Interactions between Pluronics (F127 and F68) and Bile Salts (NaTDC) in the Aqueous Phase and the Interface of Oil-in-Water Emulsions

et al. 2013

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“…In agreement with the expected different surfactant features of cholates and deoxycholates, a systematic study of the adsorption-desorption at the air-water interface was recently reported, revealing very different surface properties of taurocholate (NaTC) and glycodeoxycholate (NaGDC). Higher adsorption rates and adsorbed molecule concentration are shown by NaTC, which tends to aggregate/complex at the surface forming irreversibly adsorbed clusters [14].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Bile salts and derivatives: Rigid unconventional amphiphiles as dispersants, carriers and superstructure building blocks

Galantini

Gregorio

Gubitosi

et al. 2015

Current Opinion in Colloid & Interface Science

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“…7, hence suggesting that traces might remain adsorbed at the oil-water interface. Only recently have we deepened further into this aspect by looking in more detail into the adsorption-desorption profiles of NaTC and NaGDC at the air-water interface [34]. Interestingly, these more accurate measurements have finally demonstrated that only NaGDC fully desorbs from the air-water interface regardless of the surface coverage.…”

Section: Bile Saltsmentioning

confidence: 99%

“…Interestingly, these more accurate measurements have finally demonstrated that only NaGDC fully desorbs from the air-water interface regardless of the surface coverage. Conversely, NaTC displays a complex desorption profile as a function of surface coverage in which surface complexes seem to remain adsorbed at the surface [34]. Therefore, once again, only very recent advances in experimental techniques have allowed us to investigate in detail the adsorption-desorption profile of BS.…”

Section: Bile Saltsmentioning

confidence: 99%

“…The coaxial double capillary offers a simple tool to investigate their interfacial behaviour, which is crucial for controlling adsorption-desorption kinetics, and may influence how the bile salts interact with other molecules during the digestion process. This would hence, help to control the rate and extent of lipid digestion and the bioavailability of lipid-soluble molecules [31,34]. Another area where considerable research activity can probably be expected over the next few years is in the protein-polysaccharide mixtures.…”

Section: Future Perspectives and Conclusionmentioning

confidence: 99%

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Subphase exchange experiments with the pendant drop technique

Maldonado-Valderrama

Torcello‐Gómez

Castillo-Santaella

et al. 2015

Advances in Colloid and Interface Science

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This review aims to compile the experimental work done, using the pendant drop subphase exchange in the last decade, and how its use has provided new insights into the surface/interfacial properties of many different materials. Special emphasis is placed on recent work regarding simulation of in vitro digestion in order to address issues relating to metabolism degradation profiles. The use of this methodology when dealing with interfacial studies allows setting the foundations of interfacial engineering technology. Based on subphase exchange experiments, we aim to develop models for competitive adsorption of different compounds at the interface and build up layer-by-layer interfacial structures. Future challenges comprise the design of finely adjusted nanoengineering systems, based on multilayer assemblies with tailored functionalities, to match the application demand.

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Bile salts at the air–water interface: Adsorption and desorption

Cited by 33 publications

References 26 publications

Interactions between Pluronics (F127 and F68) and Bile Salts (NaTDC) in the Aqueous Phase and the Interface of Oil-in-Water Emulsions

Interactions between Pluronics (F127 and F68) and Bile Salts (NaTDC) in the Aqueous Phase and the Interface of Oil-in-Water Emulsions

Bile salts and derivatives: Rigid unconventional amphiphiles as dispersants, carriers and superstructure building blocks

Subphase exchange experiments with the pendant drop technique

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