Bile Flow Mechanism in Man

Ono, Katsushige; Watanabe, Noboru; Suzuki, Kazuyuki; Tsuchida, Hiroshi; Sugiyama, Yuzuru; Abo, M.

doi:10.1001/archsurg.1968.01330240015004

Cited by 42 publications

(10 citation statements)

References 3 publications

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“…In the late 1960s, Ono et al (132) sutured electrodes into the sphincter and duodenal musculature during laparotomy that was done for other reasons. Recordings after surgery showed rhythmic sphincter spike bursts that were independent of duodenal myoelectric activity.…”

Section: Humansmentioning

confidence: 99%

Motility of the biliary system

Dodds

Hogan

Geenen

1989

Comprehensive Physiology

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Section: Humansmentioning

confidence: 99%

Motility of the biliary system

Dodds

Hogan

Geenen

1989

Comprehensive Physiology

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“…The periodic interruptions of flow lasted -4-6 s, approximately the duration of the SO pressure waves. This seemingly paradoxical finding, observed also in other species (18,25), has led some workers to conclude that the function of phasic SO contractions is to retard CBD outflow (25)(26)(27). When considered further, however, emptying of fluid from the CBD into the SO segment would not be expected during forceful SO contractions, even though the SO contractions propagate toward the duodenum.…”

Section: Myoelectric Activitymentioning

confidence: 99%

Motor function of the opossum sphincter of Oddi.

Toouli¹,

Dodds²,

Honda³

et al. 1983

J. Clin. Invest.

100

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A B S T R A C T We studied the opossum sphincter of Oddi (SO) because in this species the SO is -3 cm in length and its extraduodenal location permits recording of motor activity with negligible interference from duodenal motor activity. The SO cineradiography, CBD inflow of contrast medium, SO manometry, and SO electromyography indicated that rhythmic peristaltic contractions stripped contrast medium from the SO into the duodenum. During SO systole, CBD emptying was transiently interrupted, whereas SO filling occurred during the diastolic interval between SO peristaltic contractions. SO distention increased the frequency of SO peristalsis. We conclude that (a) the dominant feature of the opossum SO is rhythmic peristaltic contractions that originate in the proximal SO and propagate toward the duodenum; (b) these forceful SO peristaltic contractions are myogenic in origin and serve as a peristaltic pump that actively empties the SO segment; (c) CBD outflow occurs passively during SO diastole, but is interrupted transiently during each SO peristaltic contraction; and (d) a short HPZ with active as well as passive components exists in the distal SO segment and acts as a variable resistor to SO outflow.

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“…Whereas Hand [1], Hess [2], Ritter [22] and Watts and Dutnphy [23] postulated an active ejaculation mecha nism of the sphincter of Oddi. Ono [24] found a passive bile flow through the papilla by the electromyographical investigation of the sphincter mechanism while the sphincter muscle was relaxed, as revealed by electro myographic potentials. Own results are in accordance with these observations.…”

Section: Discussionmentioning

confidence: 99%

Effect of the Artificially Elevated Common Bile Duct Pressure on the Motor Activity and Function of the Papilla of Vater

Staritz¹,

K²,

Büschenfelde³

1985

Digestion

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In 10 patients without disease of the pancreatico-biliary system, the common bile duct pressure was artificially elevated by endoscopic retrograde feeding with saline under manometric control. The motor activity of the papilla of Vater was recorded by endoscopic manometry using the hydraulic capillary perfusion system according to Arndorfer. Compared to the baseline motility, a mild pressure elevation (from 9.75 ± 1.8 to 13.5 ± 0.26 mm Hg) had no effect. After the following strong pressure elevation (to 32 ± 0.9 mm Hg), however, the papillary residual pressure and the wave duration of the papillary contractions increased significantly (p < 0.001) from 5.5 ± 0.5 s and 6.3 ± 0.16 mm Hg to 10.7 ± 0.75 s and 8.6 ± 0.64 mm Hg, whereas the papillary contraction frequency and amplitude were not affected. These data indicate several clinically important speculations.

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Bile Flow Mechanism in Man

Cited by 42 publications

References 3 publications

Motility of the biliary system

Motility of the biliary system

Motor function of the opossum sphincter of Oddi.

Effect of the Artificially Elevated Common Bile Duct Pressure on the Motor Activity and Function of the Papilla of Vater

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