Bilateral sclerosing stromal tumor of the ovaries in a premenarchal girl

Chang, Winston W.; Oiseth, Stanley J.; Orentlicher, Rona; Agarwal, Gautam; Yahr, Laura J.; Cayten, C. Gene

doi:10.1016/j.ygyno.2005.10.041

Cited by 39 publications

(79 citation statements)

References 8 publications

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“…This type was defined by Chalvaridjan and Scully (1973) for the first time and it is often observed in the 2 nd and 3 rd decades of life [1]. To the best of our knowledge, although this tumour has been described before in adolescents, only one paediatric case of a bilateral SST (in a 10 year old premenarchal girl) has been described in the clinical literature [12]. An overview on all case reports on SSTs which had been reported between 2003-2013, has been shown in [Table/ Fig-6].…”

Section: Macroscopic Findingsmentioning

confidence: 99%

Sclerosing Stromal Tumour in Young Women: Clinicopathologic and Immunohistochemical Spectrum

Kaygusuz

Cesur²,

Çetiner³

et al. 2013

JCDR

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Aim: Sclerosing stromal tumor is a benign tumor of ovary. We aimed to review the clinical findings and immunohistochemical results of SSTs through the 7 diagnosed cases in our hospital. Material and Methods:As immunohistochemical, blocks were applied with estrogen receptor , progesterone receptor, inhibin, calretinin, melan-A, CD10, smooth muscle actin, desmine, vimentin, CD34, S-100, C-kit, cytokeratin , cytokeratin7.Results: Macroscopically, while 5 tumors had solid appearance, 2 tumors were composed of solid and cystic areas. All the tumors were in shape of ovarian masses with good limits. Microscopically, two types of cells were observed as fusiform fibroblast-like cells and theca-like cells with vacuolised cytoplasm. Immunohistochemical results: vimentin, smooth muscle actin, desmine, progesterone receptor, calretinin, inhibin were positive in all the cases; S-100, cytokeratin, cytokeratin7, estrogen receptor were negative in all the cases; CD-10 was positive in 2 cases; C-kit was positive in 5 cases; melan-A was positive in 4 cases. Conclusions:The significance of these tumors is that it is necessary to distinguish the histopathology in the frozen section in order to protect the other adnexa because of the characteristics to be observed at early ages (2 nd and 3 rd decades).Our findings support the conclusion that sclerosing stromal tumors are benign-character tumors that stem from over stroma and are hormonally active tumors because of the detected clinical and immunohistochemical results, although no hormonal effect that could be supported with laboratory tests was observed.

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Section: Macroscopic Findingsmentioning

confidence: 99%

Sclerosing Stromal Tumour in Young Women: Clinicopathologic and Immunohistochemical Spectrum

Kaygusuz

Cesur²,

Çetiner³

et al. 2013

JCDR

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“…In most of the studies about SST, it was seen that laparotomy and salpingo oophorectomy were applied because of the suspicion of malignancy in imaging studies (6,7,11,12) . In literature, all cases were diagnosed as benign except for one patient with low grade malignancy reported in 1990 (13) .…”

Section: J Turk Soc Obstet Gynecol 2011; 8: 286-8mentioning

confidence: 99%

Sclerosing Stromal Tumor of The Ovary: A Case Report

Dilbaz¹,

Taşçı²,

Ulular³

et al. 2011

J Turk Soc Obstet Gynecol

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“…Sex cord stromal tumors represent approximately 8% of ovarian neoplasms and SSTs constitute 2.5 to 6% of the tumours with more than 80% of such tumors are found in young adult women in the second [2][3][4][5] and third decade of life.…”

Section: Introduction Case Reportmentioning

confidence: 99%