Bilateral Retinoblastoma Presenting With Simultaneous Phthisis Bulbi and Buphthalmos

Bilateral Retinoblastoma Presenting Atypically with Atrophic Bulbi and Contralateral Buphthalmos

“…Under 10 similar cases have been reported until now. 4,5 This case is unique and very rare combination of these two presenting signs in different eyes of the same child adds further to the existing scant literature pertaining to the possibility of harbouring retinoblastoma in these eyes and hence its prompt management.…”

Phthisis bulbi in retinoblastoma

“…In three case series on primary phthisis bulbi in retinoblastoma patients, reported in literature, 50–86% patients had bilateral disease 1,2,4 . Most case reports of retinoblastoma patients presenting with phthisis bulbi also report bilateral disease 6–12 . Sovik et al .…”

“…Two infants (8 months and 11 months old; case 10 and case 13) who had only 1‐month history of symptoms had group D disease in other eye. Advanced intraocular disease was found in the fellow eye of many single cases reported in literature 6,8–11 . Kao et al .…”

“…1,2,4 Most case reports of retinoblastoma patients presenting with phthisis bulbi also report bilateral disease. [6][7][8][9][10][11][12] Sovik et al reported retinoblastoma in six siblings, three of whom had phthisis bulbi with bilateral disease. 6 A total of 83% (15/18) patients in our series had bilateral retinoblastoma.…”

“…Advanced intraocular disease was found in the fellow eye of many single cases reported in literature. 6,[8][9][10][11] Kao et al in their series on retinoblastoma with phthisis bulbi, reported advanced disease in other eye in 50% (3/6) of their cases. 4 Two of these had metastatic disease (regional lymph node metastasis in one and central nervous system metastasis in one) and one had overt orbital involvement.…”