Bilateral primary ovarian non-Hodgkin�s lymphoma and fertility preservation: 5-year follow-up

Grigoriadis, C

doi:10.11138/gchir/2017.38.2.077

Cited by 5 publications

(4 citation statements)

References 8 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vang R et al reported that patients who undergo surgery, radiation, or chemotherapy have an equitable prognosis [3]. However, other experts feel that chemotherapy combined with radiotherapy, rather than signi cant surgical resection, can provide a better prognosis, and nonsurgical treatment can help the reproductive system function properly [19,20]. In any case, combinations of different regimens are needed, and single regimens are often ineffective [21].…”

Section: Discussionmentioning

confidence: 99%

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

sun,

ma,

Jiang

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Primary DLBCL of the ovary is an uncommon malignant ovarian tumor. Its pathogenesis is unclear. Clinical symptoms and auxiliary exams show little specificity. Diagnosis is difficult before surgery. It is frequently misdiagnosed as other malignant ovarian tumors. Misdiagnosis frequently leads to excessive therapy. Patient presentation A 51-year-old patient with abdominal pain for two months and an abdominal mass for one week was admitted to the hospital. The patient had no vaginal bleeding or fluid; no fever, chills, night sweats, or weight loss; and no obvious medical or family history. When a diagnosis of an ovarian malignant tumor was considered, we performed double adnexectomy plus adnexectomy, hysterectomy, greater omentectomy, and partial peritonectomy. Postoperative pathology revealed DLBCL of the ovary, an anaplastic center-like subtype. The patient subsequently received two cycles of chemotherapy with the R-CHOP regimen. The patient's condition improved after chemotherapy, with no signs of disease progression, and she was considered for continuation of chemotherapy with the original regimen. Conclusions We reviewed the patient’s clinical data and literature to improve practitioners' understanding of the disease and prevent misdiagnosis and overtreatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

sun,

ma,

Jiang

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…This is not the case for primary ovarian non-Hodgkin's lymphoma. In most publications, the median age of patients was 42 to 47 years [ 17 , 18 ], but it can occur at any age. Senol et al reported a median age of 57 years.…”

Section: Discussionmentioning

confidence: 99%

“…Other signs that have been reported include weight loss, fever, and sometimes metrorrhagia [ 9 , 14 - 15 ]. A clinical examination may find hepatosplenomegaly or palpable adenopathy [ 17 ]. In our case, the patient was diagnosed with isolated pelvic pain.…”

Section: Discussionmentioning

confidence: 99%

An Extranodal Site of Diffuse Large B-cell Lymphoma Presenting as Ovarian Cancer

Jaouani¹,

Zaimi²,

Jarroudi³

et al. 2023

Cureus

View full text Add to dashboard Cite

Due to its uncommon nature, primary ovarian lymphoma has no clinical particularities and can be confused with other ovarian cancers. It poses a twofold diagnostic and therapeutic challenge. An anatomopathological and immunohistochemical study is the crucial step in the diagnosis. Our case was a 55-year-old woman diagnosed with an Ann Arbor stage II E ovarian non-Hodgkin's lymphoma who initially presented with a painful pelvic mass. This case reflects the major role of an immunohistochemical study in the diagnosis workup, leading to the appropriate management of such rare tumors.

show abstract

“…Rituximab, a monoclonal antibody against CD20, is an immunotherapeutic agent that plays an important role in the treatment of CD20-positive B-cell lymphoma, including extranodal lymphoma [16]. Grigoriadis et al have reported that rituximab may be a better choice for patients desiring to preserve their fertility [17]. As early as 2007, Signorelli M et al proposed that a conservative management based on exclusive chemotherapy at early stages of PLFGT may be attempted in patients desiring to become pregnant [18].…”

Section: Discussionmentioning

confidence: 99%

Primary Diffuse Large B-Cell Lymphoma of Ovary: Report of Cases and Literature Review

XF¹,

XL²,

YT³

et al. 2022

annhematoloncol

View full text Add to dashboard Cite

Objective: Our study aimed to review the characters of primary diffuse large B-cell lymphoma (DLBCL) of ovary and provide recommendations of management for this rare disease. Methods: We presented 4 cases of primary ovarian DLBCL (PODLBCL) from Beijing Chaoyang Hospital between 2003 and 2021. Furthermore, we searched PubMed and Web of Science database for literature published between 1998 and 2021.A total of 16 articles included 24 cases with histopathologically confirmed PODLBCL and detailed evaluation and follow-up were reviewed. Results: The median age of patients with PODLBCL was 43y (5-73y). The main clinical symptoms were pelvic mass, abdominal pain, followed by irregular vaginal bleeding and urinary incontinence. 25% patients had bilateral ovarian tumors, and 61.1% of unilateral tumors were in the left ovary. Cancer antigen 125 (CA125) and serum lactate dehydrogenase (LDH) were usually elevated to varying degrees. Most cases were diagnosed by surgery and presented in early stage. Treatments included surgery, chemotherapy and monoclonal antibody therapy. There was no evidence of recurrence within a median follow-up time of 20 months (range 5-72 months) in 79.1% (19/21) of patients. Conclusions: PODLBCL had no significantly specific character to distinguish from ovarian epithelial malignant tumors. The prognosis of patients with PODLBCL was usually good. We proposed that chemotherapy combined with monoclonal antibody therapy may be the first-line treatment for PODLBCL, and surgical resection of the tumor may be avoided. The key problem is how to make an early preoperative diagnosis. Therefore, more case reports and institutional studies are needed to confirm these conclusions.

show abstract

Bilateral primary ovarian non-Hodgkin�s lymphoma and fertility preservation: 5-year follow-up

Cited by 5 publications

References 8 publications

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

An Extranodal Site of Diffuse Large B-cell Lymphoma Presenting as Ovarian Cancer

Primary Diffuse Large B-Cell Lymphoma of Ovary: Report of Cases and Literature Review

Contact Info

Product

Resources

About