Bilateral optic neuropathy and white dot syndrome following a mycoplasmal infection.

Cordonnier, Monique; Caspers-Velu, L; Nechel, Christian Van; Tombroff, M

doi:10.1136/bjo.77.10.673

Cited by 4 publications

(6 citation statements)

References 11 publications

(1 reference statement)

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“…Ophthalmic pathology has also been reported in the literature. Although conjunctivitis is the most frequent ocular manifestation of this pathogen [3], other complications have also been described such as third or sixth nerve palsies, homonymous hemianopia, nystagmus [4], anterior uveitis [2] and very rarely optic neuropathy with consecutive optic atrophy [4, 7, 8]. Reviewing the world literature we found 22 cases of ocular pathology following systemic infection with Mycoplasma pneumoniae .…”

Section: Discussionmentioning

confidence: 99%

“…Most of the cases reported in the literature experienced some degree of visual recovery following the resolution of disc swelling and only a few ended up with a complete optic nerve atrophy. Like our patient, the majority of these cases responded favourably to systemic steroids associated with erythromycin [7, 8], tetracyclines or rifampin; all of them have been reported to be effective against Mycoplasma pneumoniae [1]. …”

Section: Discussionmentioning

confidence: 99%

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Bilateral Optic Papillitis Following Mycoplasma pneumoniae Pneumonia

Millá

Zografos²,

Piguet³

1998

Ophthalmologica

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Mycoplasma pneumoniae is an atypical bacterium that can cause a great variety of respiratory infections and be responsible for ocular involvement such as conjunctivitis, anterior uveitis and very rarely optic neuropathy. We report herein an additional case of bilateral optic disc swelling with profound visual loss following Mycoplasma pneumoniae pneumonia and review the world literature on the ocular manifestations associated with this pathogen.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Bilateral Optic Papillitis Following Mycoplasma pneumoniae Pneumonia

Millá

Zografos²,

Piguet³

1998

Ophthalmologica

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“…Ocular manifestations other than conjunctivitis are uncommon. However, papilloedema [10] and bilateral ON have been described following an acute infection by Mycoplasma pneumoniae [1,7]. It is also well known that Mycoplasma pneumoniae infection is related to about 5 % of cases of GBS [4].…”

mentioning

confidence: 98%

Bilateral optic neuritis and Guillain-Barr� syndrome following an acute Mycoplasma pneumoniae infection

et al. 2004

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“…To our knowledge, the present study is the largest trial demonstrating VEP pathologies in adult GBS patients. Previously reported VEP abnormalities in GBS patients are absent VEPs, 28 P100 elongation, 7 , 20 , 24 , 27 , 33 , 34 N145 latency elongation, 5 and alterations in P100 morphology. 25 P100 latencies differed significantly between the two sides in all of our patients with pathologic VEPs, suggesting that if it is present, optic-nerve or postchiasmal involvement is always asymmetric.…”

Section: Discussionmentioning

confidence: 82%

“…Involvement of the second cranial nerve in GBS may be related to infectious agents such as Mycoplasma pneumoniae, 17 , 18 , 25 , 34 cytomegalovirus, 3 Epstein-Barr virus, 28 mumps virus, 37 and herpes simplex virus type I. 20 Isolated optic neuritis may develop after mycoplasma infection.…”

Section: Discussionmentioning

confidence: 99%

Visual Evoked Potentials in Guillain-Barré Syndrome

Güngör

Öztürk

et al. 2011

J Clin Neurol

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Background and PurposeGuillain-Barré syndrome (GBS) is an acute demyelinating polyneuropathy with various clinical features. Optic neuritis occurs in rare cases. In this study we determined the incidence and patterns of visual evoked potential (VEP) abnormality in GBS in association with ophthalmologic findings.MethodsThirty-two patients with a diagnosis of GBS were included in the study. The correlation between pathologic VEPs and categories of neurologic deficit and electrophysiological findings were examined statistically.ResultsThe patients ranged in age from 19 to 77 years. Five cases (16%) had abnormal VEPs. All five of these patients exhibited increased P100 latency differences between the two eyes. Other abnormalities were prolonged p100 latency, increased interocular amplitude difference, and distorted p100 configuration. Pathologic signs on ophthalmologic examination were observed in 80% of patients with abnormal VEPs. VEP abnormality was never present in pure axonal forms. There was no significant correlation between pathologic VEP and cerebrospinal fluid protein level or categories of neurologic deficits.ConclusionsInvolvement of the optic pathways is not a frequent finding in GBS. When present it is always asymmetric and generally accompanied with pathologic findings on ophthalmologic examination. VEPs may be abnormal in different clinical variants of GBS, and especially in demyelinating forms.

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Bilateral optic neuropathy and white dot syndrome following a mycoplasmal infection.

Cited by 4 publications

References 11 publications

Bilateral Optic Papillitis Following Mycoplasma pneumoniae Pneumonia

Bilateral Optic Papillitis Following Mycoplasma pneumoniae Pneumonia

Bilateral optic neuritis and Guillain-Barr� syndrome following an acute Mycoplasma pneumoniae infection

Visual Evoked Potentials in Guillain-Barré Syndrome

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