Bilateral dentigerous cysts that involve all four dental quadrants: a case report and literature review

Abstract

Dentigerous cysts are common odontogenic cysts that are associated with the crown of the tooth and typically develop from single lesions. Bilateral and multiple dentigerous cysts are very rare and occur in patients with syndromic conditions. This paper presents a case report of a 15-year-old male patient that experienced non-syndromic bilateral dentigerous cysts that simultaneously occurred in all four dental quadrants around the unerupted third molars. Clinicians should confirm the extent of cystic lesions using a panoramic view and computed tomography, and should keep the possibility of bilateral dentigerous cysts in mind as a potential diagnosis, even in a non-syndromic patient.

Bilateral Maxillary Dentigerous Cysts in a Nonsyndromic Child: A Rare Presentation and Review of the Literature

“…DCs usually occur solitarily in most instances, and bilateral occurrence is an extremely rare finding. Bilateral and multiple DCs have been reported to occur in association with the number of syndromes or systemic diseases including basal-cell nevus syndrome, Gardner's syndrome, Maroteaux–Lamy syndrome (mucopolysaccharidosis type IV), cleidocranial dysplasia, and Klippel–Feil syndrome [ 3 – 6 ]. Sometimes, this entity is induced by prescribed medications like the combined use of cyclosporine A and calcium channel blockers [ 2 , 4 ].…”

“…It accounts for nearly 24% of all the true cysts in the jaws, thus being only the second most common to radicular cysts in the frequency of occurrence [ 1 , 2 ]. The usual presentation is that of a solitary lesion; however, in the presence of developmental syndromes or systemic diseases or the concurrent use of certain drugs, bilateral or multiple lesions are seen to occur [ 3 – 6 ]. Having said that, the occurrence of the bilateral DC in the absence of any of these factors is an extremely rare occurrence.…”

“…The authors believe that this is one of the only four cases to have presented in the maxilla bilaterally and therefore needs a special mention. In fact, the review of existing English literature and extensive search on PubMed database from 1943 to 2017 brought to light a total of 30 cases of the bilateral DC, 3 of which have been reported in the maxilla so far, while 24 have been reported in the mandible and the remaining 3 in both the maxilla and the mandible [ 2 , 6 ]. These statistics only point towards the true rarity of the condition.…”

Multiple Dentigerous Cysts: two case reports of nonsyndromic twins

“…5 Although some authors believe that multiple and bilateral DCs are rare in the absence of developmental syndromes, 9 many cases of multiple DCs in nonsyndromic patients have previously been reported. [10][11][12] We present the case of nonsyndromic twins with multiple DCs, a condition that, to our knowledge, has not been previously reported.…”

Clinical and Histopathological Study of Dentigerous Cyst Associated to Maxilar Lateral Tooth: Case Report

“…El tratamiento del QD incluye varias opciones entre ellas eliminación de la lesión del diente afectado, la enucleación de la patología y remoción de diente afectado o marsupialización, siendo este último el de elección para prevenir su recurrencia (2,12,20,21).…”