Bilateral connate fistula of the lower lip

Csiba, A

doi:10.1016/0030-4220(66)90284-2

Cited by 13 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many authors believe that there is a greater prevalence in women, due to their greater concern for aesthetic defects (Onofre et al, 1997;Watanabe et al, 1951). Our study indicates that the frequency of the syndrome in men is much higher than in women, accounting for 80% of the cases, coinciding with the study by Csiba et al, although he found that the syndrome is twice as frequent in males than in females (Csiba, 1966).…”

Section: Craniofacial Characterization Of the Vws Patientssupporting

confidence: 92%

Craniofacial characteristics in Van der Woude syndrome

et al. 2022

View full text Add to dashboard Cite

The Van der Woude syndrome (VWS; OMIN #119300) is a rare dysmorphic disease of genetic origin (Dissemond et al., 2004). It is characterized by the presence of lower lip pits in relation to the cleft lip and/or palate (Dissemond et al., 2004) and it is the most frequent form of syndromic clefting, accounting for 2% of all cleft lip and palate cases [prevalence 1:40000 to 1:100000 live births].Furthermore, there are no significant differences between sexes (Cervenka et al., 1967;Rizos & Spyropoulos, 2004).

show abstract

Section: Craniofacial Characterization Of the Vws Patientssupporting

confidence: 92%

Craniofacial characteristics in Van der Woude syndrome

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The histopathological studies under light microscope have shown that the fistula's wall is covered in all its depth, with few exceptions, by stratified nonkeratinized squamous epithelium 2,4,6,7,13,16,20,21,24,27 .…”

Section: Discussionmentioning

confidence: 99%

Ultrastructural analysis of glands located in the wall of the congenital fistulae of the lower lip of patients with Van der Woude syndrome

2003

View full text Add to dashboard Cite

The objective of the present study was to evaluate the glands of wall of congenital fistulae of the lower lip with the transmission electron microscope in order to characterize their microstructural pattern. Thin section of Araldite resin embedded congenital fistulae of the lower lip of four patients with Van der Woude syndrome from the Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo, Bauru, SP, were analyzed with a transmission electron microscope. The results showed that the glands were mostly made by typical mucous acini exhibiting, with certain frequency, myoepithelial cells surrounding them. In some of lobules, a few acini smaller than the typical mucous, showed granules of moderate electron density or containing a dense core or exhibiting small dense spherule and predominance granular material. These granules resemble to described recently by others in various human minor salivary glands. We concluded that glands associated with congenital fistula of lower lip of patients with Van der Woude syndrome, in spite of being located in vermilion border of the lip, showed at the transmission electron microscope characteristics of labial minor salivary gland, i.e, are mostly mucous with a few seromucous units, while typical seromucous demilunes are not present.

show abstract

“…Fistulas are located in the upper border of the lower lip, in any area of the red border on the mucous portion of the lip, with an anterior posterior direction. Major part of the pits is in the lip and in the mucocutaneous line with a distance of 5 to 25 mm between each other [10]. The base of the fistula can be found incorporated in skeletal muscle bundles, which fibers, in some sections, are oriented suggesting a peristaltic projection of the mucous secretion when contracted [11].…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…Phenotypic characteristics of VWS are essential for differential diagnosis, since there are symptoms frequently associated to VWS alone. Hypodontia é considered a typical sign of VWS and it has been observed in 10-81% of all VWS patients [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23], where the number of missing teeth in the maxilla is almost twice the number of the missing teeth in control groups [24].…”

Section: Diagnosismentioning

confidence: 99%