Bilateral chronic fungal dacryocystitis caused by<i>Candida dubliniensis</i>in a neutropenic patient: Figure 1

Roy, Anitha; Bates, V; Sandy, C

doi:10.1136/jcp.2005.027540

Cited by 7 publications

(2 citation statements)

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“…It has also been recovered from HIV-negative patients with oral candidiasis and from women with vaginitis [8]. The first case of C. dubliniensis involving the eye was described in a HIV-negative woman with bilateral chronic fungal dacryocystitis [9]. C. dubliniensis has a worldwide distribution and most isolates are susceptible to amphotericin B and azoles [10].…”

Section: Discussionmentioning

confidence: 98%

Candida dubliniensis endophthalmitis: first case in North America

et al. 2012

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To report an unusual case of endogenous fungal endophthalmitis due to Candida dubliniensis. Interventional case report of a 27-year-old immunocompetent male with loss of vision, dense vitritis, and chorioretinal infiltrates, who underwent a diagnostic pars plana vitrectomy. Microbiology cultures obtained by a diagnostic vitrectomy were positive for the growth of C. dubliniensis. This infectious process was then appropriately treated with intravitreal amphotericin B and systemic fluconazole with resolution of the endophthalmitis. Endogenous fungal endophthalmitis is a condition that can masquerade other more common causes of endophthalmitis. Atypical cases of endophthalmitis may benefit from diagnostic pars plana vitrectomy for prompt diagnosis and treatment.

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Section: Discussionmentioning

confidence: 98%

Candida dubliniensis endophthalmitis: first case in North America

et al. 2012

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“…In the ophthalmology literature, C. dubliniensis was first described as a cause of fungal dacryocystitis [ 13 ] but has more recently been described as an emerging cause of endophthalmitis [ [2] , [3] , [4] , [5] , [6] , [7] ]. It has specifically been linked to several cases of endogenous endophthalmitis in IV drug users [ [3] , [4] , [5] , [6] ].…”

Section: Discussionmentioning

confidence: 99%

Candida dubliniensis: A novel cause of fungal keratitis

Oostra

Schoenfield

Mauger

2018

IDCases

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A 45-year-old female with history of contact lens wear presented with a persistent corneal ulcer that was unresponsive to topical moxifloxacin. The patient’s exam was concerning for fungal keratitis. Cultures were obtained, and the patient was started on fortified amphotericin B drops and oral voriconazole. The cultures identified Candida dubliniensis as the causative organism. The patient’s exam worsened despite treatment, and the decision was made for surgery. At the time of surgery, her cornea was found to have unexpectedly perforated. She underwent cryotherapy; tectonic penetrating keratoplasty; anterior chamber tap; intracameral voriconazole, amphotericin B, and cefuroxime; and a partial conjunctival flap. Pathology from the cornea showed GMS and PAS stains positive for fungal forms.C. dubliniensis is a yeast closely related to Candida albicans that was first described in 1995 as a cause of oral candidiasis in patients with AIDS. There are a few published cases of endophthalmitis due to C. dubliniensis in the ophthalmology literature, but to our knowledge, no cases of fungal keratitis due to this organism have been reported. C. dubliniensis is a novel cause of fungal keratitis that can be difficult to identify and treat but is felt to be less virulent than C. albicans and generally susceptible to available anti-fungal therapies.

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