Bilateral Calcifying Cystic Odontogenic Tumour of Mandible: A Rare Case Report and Review of Literature

Abstract

Calcifying cystic odontogenic tumour (CCOT) is a relatively rare lesion of oral and maxillofacial region and forms only 2% of all odontogenic tumours. It was previously known as Calcifying odontogenic cyst and only recently has been classified as a tumour by WHO. The controversy regarding its origin can be owed to its diverse clinical and histopathological presentation and variation in reported malignant potential. It was first reported by Gorlin in 1962 and since then conundrum regarding its true nature has persisted. It is seen in association with other lesions like odontoma, ameloblastoma and ameloblastic fibroma. Both intra-osseous and extra-osseous forms of CCOT have been reported. It commnoly occurs in anterior region with equal preponderance in maxilla and mandible. Here we present a rare case of bilateral CCOT in the posterior mandible of a 16-year-old male patient which was discovered incidentally during a radiographic examination.

Calcifying odontogenic cyst associated with complex odontoma treated with a conservative approach: a case report / Cisto odontogênico calcificante associado a odontoma complexo tratado com abordagem conservadora: relato de caso

“…Thus, as the lesion included tooth 13, extended into the amelo-cementary junction, and was located in the anterior region of the maxilla, we made a diagnosis of TOA [8]. Even though radiography is a tool for the diagnosis of COCs, it has insufficient pathognomonic characteristics to guide the final resolution of the case, which is dependent on histopathological examination [12].…”

Calcifying odontogenic cyst: A case report

“…It is this unique feature that also differentiates it from an ameloblastoma. However, the synchronous occurrence of COC with ameloblastomas and other odontogenic pathologies including dentigerous cysts, ameloblastic fibromas and odontomas has been reported. COCs are complex lesions and can have substantial variation in the morphology of the epithelium, with several different lesions incorporated, including other odontogenic cysts and/or tumours.…”

Developmental odontogenic cysts with special focus on the occurrence of multiple cysts: a single-centre retrospective study from the Czech Republic

“…Even a case simultaneously presenting an OKC and bilateral DC was reported [24]. Other multiple DOCs, such as multiple OOCs [25,26], BCs/LPCs [27], COCs [28,29], and GOCs [30,31] are very rare and, to the best of our knowledge, are not associated with any syndrome. This retrospective study aimed (i) to evaluate the distribution of various types DOCs in patients presenting with these cysts over the last ten years in a large university hospital in the Czech Republic serving a population of approx.…”