Biheterocyclic ligands: synthesis, characterization and coordinating properties of bis(4-amino-5-mercapto-1,2,4-triazol-3-yl) alkanes with transition metal ions and their thermokinetic and biological studies

Abstract

Abstract:The Co(II), Ni(II) and Cu(II) metal ions complexes of Bis (4-amino-5-mercapto-1,2,4-triazol-3-yl) alkanes (BATs) have been prepared and characterized by elemental analysis, conductivity measurements infrared, magnetic susceptibility, the electronic spectral data and thermal studies. Based on spectral and magnetic results, the ligands are tetradentate coordinating through the N and S-atoms of BATs; six-coordinated octahedral or distorted octahedral and some times four-coordinated square planar were proposed for these complexes. Activation energies computed for the thermal decomposition steps were compared. The ligands and their metal complexes were tested in vitro for their biological effects. Their activities against two gram-positive, two gram-negative bacteria and two fungal species were found to vary from moderate to very strong.

Synthesis and characterization of transition metal complexes of 4-Amino-5-pyridyl-4H-1,2,4-triazole-3-thiol

“…Amine and thione-substituted triazoles have been studied as anti-inflammatory and anti-microbial agents and other applications (Awad et al, 2008). Triazole are considered to be good coordinating ligands (Al-Maydama et al, 2008), because they involved both hard nitrogen and soft sulfur atom as thio amide group. This ligand have doner group that coordinate with wide range of metal ions (Narayana and Gajendragad, 1997).…”

Synthesis and Spectroscopic Studies of some Divalent Metall Ion Complexes of 3-(4-hydroxyphenyl)-2-(3-(4-nitrobenzoyl) thioureido) propanoic acid

“…The stretching vibration band υ(C=O) amid and υ(C=S) either show no change or very little in their frequencies (1620-1604)cm -1 ,(1230-1280)cm -1 ,respectively; therefor, indicating do not coordinate to the metal ion. Metal-oxygen and metal-nitrogen were confirmed by the presence of the stretching tremor of υ(M-N) and υ(M-O) around (443-466)cm -1 and (428-401)cm -1 respectively [15]. Table (2) describes the important bands and assignment for all prepared complexes.…”

Study The Rate Constant of Photodecomposition of Polystyrene Films in Presence of Some 4- amino-5-(2-(6-methoxynaphthalen-2-yl)piperidino)-1,2,4- triazole-3-thion Complexes

“…[4-amino-5-(2-(6methoxynaphthalen-2-yl)piperidino)-1,2,4triazole-3-thion and matel complexes was prepared by the method previously described [11] as in Fig. (1).…”

“…Triazoles are five memberd heterocyclic compounds containing three nitrogen and two carbon atoms. The substituted triazole with sulphur atom and amine group are considered to be good coordinating ligands because they involved both hard nitrogen and soft sulfur atom as thio amide group, this ligand have doner group that coordinate with wide range of metal ions [1,2]. In this paper some complexes of substituted 1,2,4 triazol with thio and amino group has been used as photostabilizer for polystyrene.…”