“…We have previously developed a “Big Events” framework for research and interventions on pandemics, including zoonotic pandemics, that create, or occur under, situations of social emergency and interact with pre-existing social structures and processes [ 14 , 15 ]. We developed this perspective out of analysis of HIV/AIDS outbreaks that took place in the countries of the former Soviet Union after the dissolution of the USSR; in South Africa after the end of apartheid; and in Indonesia after the economic crisis and overthrow of the dictatorship in the late 1990s [ 7 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ].…”