Bifrontal Epidermoid Cyst

Abstract

In this paper, we will present a case of a 63-year-old female with bifrontal epidermoid tumor who has gone under bilateral craniotomy. In a case report study, a 63-year-old female with a chief complaint of progressive headache that has been admitted to Department of Neurosurgery was studied. Magnetic resonance imaging was performed for better evaluation. After detection of bifrontal epidermoid cyst, the patient underwent surgery, and following the surgery, a cut of the tumor has been excised, sent for pathology sampling and reviewed for detection of cyst. Microscopic review of the resected part reported normal brain tissue along with sections containing parts of cyst wall covered by squamous epithelium and huge amount of irregularly stratified keratin within its lumen, which clearly emphasizes on diagnosis of a typical epidermoid tumor. Bifrontal epidermoid cyst is rare, and according to our study, the clinical symptoms and patients imaging were consistent with other studies.

Rapid malignant transformation of an intracranial epidermoid cyst: Report of a case

“…1 ECs tend to commonly occur at the cerebellopontine (CP) angle, parasellar and suprasellar regions, spinal canal, and posterior fossa, with a predilection for intradural, extra-axial and paramedian cisternal spaces. 2 Owing to their benign nature, they are often slow growing and generally manifest in adults after 40 years of age. 3 Depending on their location, patients with ECs can present with headache, raised intracranial tension, and cranial neuropathies, among other symptoms.…”

“…During three to five weeks of embryogenesis, incomplete cleavage of the neural ectoderm from the cutaneous ectoderm results in inclusion of the latter in the developing neural tube, which gives rise to intracranial ECs (IECs) 1 . ECs tend to commonly occur at the cerebellopontine (CP) angle, parasellar and suprasellar regions, spinal canal, and posterior fossa, with a predilection for intradural, extra‐axial and paramedian cisternal spaces 2 . Owing to their benign nature, they are often slow growing and generally manifest in adults after 40 years of age 3 .…”

A Good Aesthetic Outcome After Gross Total Tumor Resection in Combination With the Skull Reconstruction on Giant Epidermal Cyst Involving Both Intracranial and Extracranial Tissues

“…The cranial epidermoid cysts (CECs) are mostly benign, slow-growing, and congenital tumors derived from aberrant ectodermal remnants during embryogenesis, accounting for 0.2% to 1% of all the intracranial tumors 1 . Since the predilection site of CECs is the cerebellopontine angle, 2 thereby it is hard to notice their presence at the cranial region, as some of them neither cause skull lesions nor neurological symptoms 3 . Therefore, it is very uncommon to observe a giant CEC located in the frontal region with both intracranial and extracranial extension.…”