Bifocal contact dermatitis following a temporary tattoo

Tounouga, Dahlia Noëlle; Nansseu, Jobert Richie; Kouotou, Emmanuel Armand

doi:10.1002/ccr3.6470

Cited by 1 publication

(1 citation statement)

References 10 publications

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“…Chronic complications are mainly allergic reactions that occur especially with red tattoos. Allergic contact dermatitis is a common inflammatory skin disorder produced by exposure to non-protein chemical molecules [10,11]. Another complication is the Koebner phenomenon, which occurs in approximately 25% of patients with psoriasis, who experience the appearance of new psoriatic lesions after tattoos.…”

Section: Introductionmentioning

confidence: 99%

A Novel Approach for Dermal Application of Pranoprofen-Loaded Lipid Nanoparticles for the Treatment of Post-Tattoo Inflammatory Reactions

De Grau-Bassal,

Mallandrich,

Sosa

et al. 2024

Pharmaceutics

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Recently, the number of people acquiring tattoos has increased, with tattoos gaining significant popularity in people between 20 and 40 years old. Inflammation is a common reaction associated with tattooing. The purpose of this study was to evaluate a nanostructured lipid carrier loading pranoprofen (PRA-NLC) as a tattoo aftercare formulation to reduce the inflammation associated with tattooing. In this context, the in vitro drug release and the ex vivo permeation-through-human-skin tests using Franz cells were appraised. The tolerance of our formulation on the skin was evaluated by studying the skin’s biomechanical properties. In addition, an in vivo anti-inflammatory study was conducted on mice skin to evaluate the efficacy of the formulation applied topically after tattooing the animals. PRA-NLC showed a sustained release up to 72 h, and the amount of pranoprofen retained in the skin was found to be 33.48 µg/g/cm2. The formulation proved to be well tolerated; it increased stratum corneum hydration, and no signs of skin irritation were observed. Furthermore, it was demonstrated to be non-cytotoxic since the cell viability was greater than 80%. Based on these results, we concluded that PRA-NLC represents a suitable drug delivery carrier for the transdermal delivery of pranoprofen to alleviate the local skin inflammation associated with tattooing.

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Section: Introductionmentioning

confidence: 99%