Biflavanoids and a flavanone-chromone from the leaves of Garcinia dulcis(Roxb.) Kurz

Abstract

Biflavanoids and a Flavanone-Chromone from the Leaves of Garcinia du/cis (Roxb.

Kaennacowanols A–C, three new xanthones and their cytotoxicity from the roots of Garcinia cowa

“…This plant has been an abundant source of secondary metabolites, especially xanthones [2][3][4][5][6], phloroglucinols [6][7][8][9][10], flavonoids [3,11,12] and terpenoids [12,13]. Xanthones are well recognized as chemotaxonomic markers for plants of the Garcinia species [2][3][4][5][6][14][15][16][17][18] and many of which have interesting pharmacological activities, including antimicrobial [2,6], antiinflammatory [11], antimalarial [19], antioxidant [2,4,11] and cytotoxic activities [5,20]. Many parts of G. cowa have been used in traditional folk medicine.…”

Diuretic and Hypotensive Effect of Morelloflavone from Garcinia dulcis in Two-Kidneys-One-Clip (2K1C) Hypertensive Rat

“…Morelloflavone, a biflavonoid comprising two covalently linked flavones, apigenin and luteolin, occurs in most Garcinia species (Ansari et al 1976;Verbeek et al 2004). Several biological actions have been reported for morelloflavone.…”

“…Urine flow rate was determined gravimetrically by collecting urine into pre-weighed tubes and assuming a FIGURE 1. Chemical structure of morelloflavone purified from Garcinia dulcis fruits, a biflavonoid comprising two colavently linked flavones, apigenin and luteolin (Molecular formula C 30 H 20 O 11 , Molecular weight 556) (Ansari et al 1976) ANIMALS AND EXPERIMENTAL DESIGN Male Wistar rats (body weight 175±4 g, n=84) were obtained from the Southern Laboratory Animal Facility (Prince of Songkla University, Thailand). Rats were housed under control conditions (temperature 23-24°C; humidity 50-55%; lighting 0600-1800 h), fed a laboratory diet containing 34.2 mmol sodium chloride/kg dry weight food and were allow free access to reverse osmosis water.…”

Screening for Tyrosinase Inhibitors among Extracts of Seashore Plants and Identification of Potent Inhibitors fromGarcinia subelliptica

“…10) ]: FAB-MS m=z: 671 ðM þ HÞ þ , 490. Structural identification of both compounds 1 and 2 was carried out mainly by comparing of 1 H-NMR, 11,12) 13 C-NMR, 13) and MS data 10) with those reported and respectively found to be identical with structurally known biflavonoids 1 {5,7,4 0 ,5 00 ,7 00 ,3 000 ,4 000 -heptahydroxy flavanone [3][4][5][6][7][8] 00 ] flavone which has been named fukugetin 8) or morelloflavone 11) } and 2 {5,7,4 0 ,5 00 ,7 00 ,3 000 ,4 000 -heptahydroxy [3][4][5][6][7][8] 00 ] biflavanone which has been named Gb-2a 11) }. Determination of the configuration of flavanone [3][4][5][6][7][8] 00 ] flavones has recently been comprehensively reported by Li et al…”