“…High doses and repetitive use of AASs can have various adverse effects on multiple organs and systems including, but not limited to, the cardiovascular, hepatic, dermatologic, musculoskeletal, reproductiveendocrine, and even psychiatric [46]. For example, there have been several reported cases of upper and lower extremity tendon rupture [17,19,43,61,63,72], which may be caused by increased forces being transmitted from the hypertrophied musculature to tendon. Anabolic steroids may alter tendon crimp morphology, which can affect risk of tendon rupture [40].…”