Bibliometric Insights in Genetic Factors of Substance-Related Disorders: Intellectual Developments, Turning Points, and Emerging Trends

Abstract

Substance-related disorders are a group of medical conditions that affect a person's brain and behavior and lead to an inability to control the use of legal or illegal drug(s) or medication. Substance-related disorder is a serious public health and society problem worldwide. Genetic factors have been proven to have an important role. Researchers have carried out a lot of work in this field, and a large number of research results have been published in academic journals around the world. However, there are few overviews of research progress, presentation, and development trends in this field. In this study, a total of 636 articles related to genetic factors of substance-related disorders were retrieved from the Web of Science (WoS) database from 1997 to 2018, and the scientific literatures were analyzed by bibliometrics. The study found that the United States (US) has maintained a leading position in the field of research, with many core institutions and plenty of high-quality research results. Alcohol use disorder is still the most concerning issue in this field. Over the past 20 years, new techniques such as genome-wide association study (GWAS) based on high-throughput sequencing technology have replaced family studies, twin studies, and retrospective studies in this field. We believe that it is urgent to study the genetic factors of substance-related disorders, which can greatly deepen the understanding of the pathogenesis of substance-related disorders and may provide potential targets for precise treatment of such diseases.

Studies of SUD and MDDs effect on decision-making based on the drift diffusion model

“…Some brand new approaches to the study of MDD and SUD also appeared, such as approaching them with bibliometric analysis [10,11].…”

A Bibliometric Analysis of Global Scientific Literature on Substance Abuse among School Students Based on PubMed Database (1991-2021)

“…Medical Subject Headings (MeSH) list established by the National Library of Medicine; USA was referred to get the accurate search terms. Previous studies (Khalili et al, 2018;Sweileh et al, 2014;Tran et al, 2019;Wang et al, 2021 ) related to substance use disorders were also used to select the relevant search terms. The list of search terms was finalized through a discussion with a senior medical librarian, who is an expert in searching PubMed database.…”

“…Some studies would be bibliometric analyses on health informatics (Binkheder et al, 2021(Binkheder et al, ), breast cancer, (Özen Çınar, 2020, hypertension (Devos & Menard, 2019), income and cardiovascular disease (Ding et al, 2020), and Covid-19 (Chahrour et al, 2020). Some bibliometric studies were carried out related to substance abuse; for example, Bibliometric analysis of substance use disorders in Arab countries (Sweileh et al, 2014); Genetic factors of substance-related disorders (Wang et al, 2021); twenty years analysis on Illicit drug addiction (Khalili et al, 2018); substance use disorder and treatment (Tran et al, 2019); Drug abuse in India; (Azmi & Abbas, 2018); and Publications on Opioids (Azmi & Abbas, 2018). However, based on the knowledge of the author, no bibliometric study was conducted on the specific topic of substance abuse among school children.…”