Bibliography

Charney, William; Herzog, Hershel L.

doi:10.1016/b978-1-4832-2718-4.50010-0

Cited by 18 publications

(2 citation statements)

References 85 publications

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“…The production of antibodies, in addition to antigens, by cancer cells (36, 37). This work has been confirmed by Garb (38), by Charney (39, 40) and by Holmgren (41), and has received support from studies by Fahey et al (42), Moore et al (43) and Tanigaki et al (44). The presence of serum antibodies directed against cancer‐specific antigens (45).…”

Section: Introductionsupporting

confidence: 62%

“…The detection of the disease, rather than immunity to it, required an extension of concept and method. Reference has been made earlier to the presence of antibodies in cancer cells from non-immunocompetent tissues (36)(37)(38)(39)(40)(41). Evidence for the immunological competence of cancer cells was presented by Makari at the Fourth International Congress of Allergology (37) .…”

mentioning

confidence: 99%

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The Intradermal Cancer Test (Ict)*

Makari¹

1969

J American Geriatrics Society

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A reliable test for the early detection of cancer is much to be desired and has long been sought. The Intradermal Cancer Test (ICT) is based upon immunological principles, and according to the author's findings, is not influenced by certain non‐neoplastic diseases or physiological changes. The author first reported his work in 1955, and in the ensuing years has accumulated data on 995 subjects. He concludes that the test can detect early cancer, and that it is specific, reproducible and practical. The data are presented here with the hope that other research workers in this field will be encouraged to inquire further into the methods outlined in this article.

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Section: Introductionsupporting

confidence: 62%

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confidence: 99%

The Intradermal Cancer Test (Ict)*

Makari¹

1969

J American Geriatrics Society

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Microbial Transformations

Sebek¹,

Rosazza²

2000

Kirk-Othmer Encyclopedia of Chemical Technology

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The technology of microbial transformations is concerned with harnessing the enzymes of microorganisms to catalyze useful reactions of organic compounds. Microbial enzymes are well known for their abilities to hydrolyze, oxidize, reduce, and otherwise change the structures of organic chemicals. This review summarizes important historical applications of microbes to transform steroids, amino acids, antibiotics, sugars, and others structural classes of compounds and introduces applications of microorganisms and their enzymes as reagents in synthetic organic chemistry. It covers reactions including oxidations (hydroxylation, dioxygenation, dehydrogenation, β‐oxidation, and Baeyer‐Villiger oxidation), reductions (of ketones, double bonds, and carboxylic acids), hydrolyses (esters, amides, and nitriles), condensations (acyloin, aldolase, and carboxylation), amination and deamination, dehydration, N ‐ and O ‐dealkylation, decarboxylation, conjugations ( N ‐acetylation, O ‐phosphorylation, and O ‐adenylylation) and isomerization. The methodology of microbial transformations is also described. Vol. 16, pp. 611–627, 100 refs. to September 1993.

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Microbial Transformations

Michels

Khmelnitsky

Rich³

2005

Kirk-Othmer Encyclopedia of Chemical Technology

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Practical applications of microbial biotransformations to organic synthesis of a wide range of important commercial chemicals is reviewed. Specific examples of recent advances in industrial applications of biocatalysis and drug metabolite production are highlighted. Major types of chemical reactions efficiently catalyzed by microbial catalysts are summarized and reviewed, with specific examples of biotransformations applied for important synthetic processes. An emphasis is given to specific practical aspects of conducting microbial transformations, providing guidelines for successful technical implementation of synthetic reactions catalyzed by microorganisms. Covered topics include selection and handling of microbial catalysts, miniaturization and automation of microbial culture screening, and application of modern experimental techniques for analysis of microbial reactions. Additional focus is placed on formulation of microbial reaction systems to achieve optimal performance and yields, and general approaches to biotransformation scale‐up.

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Bibliography

Cited by 18 publications

References 85 publications

The Intradermal Cancer Test (Ict)*

The Intradermal Cancer Test (Ict)*

Microbial Transformations

Microbial Transformations

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