“…In any case, enterotoxic E. coli are highly infectious and cause rampant epidemics among calves, piglets, and poultry, with substantial economic losses, as well as serious outbreaks in hospital nurseries. Although the transfer from animals to man of such strains or of enterotoxigenic plasmids has not been demonstrated directly, a number of food-borne outbreaks of E. coli diarrhea due to enterotoxigenic strains have occurred (Sack et al, 1977;0rskov et al, 1977). In view of the usual animal source of food-borne coliforms, it is likely that animals were responsible here also.…”