Beyond the core face-processing network: Intracerebral stimulation of a face-selective area in the right anterior fusiform gyrus elicits transient prosopagnosia

Jonas, Jacques; Rossion, Bruno; Brissart, Hélène; Frismand, Solène; Jacques, Corentin; Hossu, Gabriela; Colnat-Coulbois, Sophie; Vespignani, Hervé; Vignal, Jean–Pierre; Maillard, Louis

doi:10.1016/j.cortex.2015.05.026

Cited by 76 publications

(45 citation statements)

References 82 publications

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“…Neuroimaging studies in humans have shown that a homologous face-selective anterior temporal region represents individual face identities in an image-invariant fashion that is also largely tolerant to changes in head rotation (Anzellotti, Fairhall, & Caramazza, 2013). Evidence for a causal role of this region in perceptual face processing comes from the observation that intracranial electrical stimulation of a face-selective region in the right anterior temporal lobe caused transient prosopagnosia, similar to the effects of OFA stimulation previously discussed (Jonas et al, 2015). Along similar lines, two patients with focal lesions to the anterior temporal lobe showed visual-perceptual deficits in both face identity matching and in matching the configuration of random dot patterns (Olson et al, 2015).…”

Section: The Neural Architecture Of the Face Processing Systemmentioning

confidence: 85%

The Cognitive and Neural Basis of Developmental Prosopagnosia

Towler

Fisher

Eimer

2017

Quarterly Journal of Experimental Psychology

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Developmental prosopagnosia (DP) is a severe impairment of visual face recognition in the absence of any apparent brain damage. The factors responsible for DP have not yet been fully identified. This article provides a selective review of recent studies investigating cognitive and neural processes that may contribute to the face recognition deficits in DP, focusing primarily on event-related brain potential (ERP) measures of face perception and recognition. Studies that measured the face-sensitive N170 component as a marker of perceptual face processing have shown that the perceptual discrimination between faces and non-face objects is intact in DP. Other N170 studies suggest that faces are not represented in the typical fashion in DP. Individuals with DP appear to have specific difficulties in processing spatial and contrast deviations from canonical upright visualperceptual face templates. The rapid detection of emotional facial expressions appears to be unaffected in DP. ERP studies of the activation of visual memory for individual faces and of the explicit identification of particular individuals have revealed differences between DPs and controls in the timing of these processes and in the links between visual face memory and explicit face recognition. These observations suggest that the speed and efficiency of information propagation through the cortical face network is altered in DP. The nature of the perceptual impairments in DP suggests that atypical visual experience with the eye region of faces over development may be an important contributing factor to DP.

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Section: The Neural Architecture Of the Face Processing Systemmentioning

confidence: 85%

The Cognitive and Neural Basis of Developmental Prosopagnosia

Towler

Fisher

Eimer

2017

Quarterly Journal of Experimental Psychology

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“…A third, more anterior face-selective area located in the fusiform gyrus between mFus and the ATL-FA was reported by Rossion et al (2012). Signal dropoff makes this a challenging area to identify using fMRI, but intracerebral recordings in a patient indicate that the region is highly selective for faces ( Jonas et al 2015), and intracranial stimulation of it severely disrupted the patient's ability to recognize famous faces ( Jonas et al 2015).…”

Section: Additional Face-selective Areas In the Temporal And Frontal mentioning

confidence: 89%

“…Transcranial magnetic stimulation (TMS) of the right occipital face area (OFA), which resides in a region close to the surface of the brain, typically disrupts face perception, whereas TMS of neighboring regions does not (Pitcher et al 2007(Pitcher et al , 2009; but see Pitcher et al 2012). Similarly, intracranial stimulation of the right OFA ( Jonas et al 2014) and face-selective regions of the right fusiform gyrus ( Jonas et al 2015, Rangarajan et al 2014 appears to selectively disrupt face perception, although the effect on nonface perception has not been compared rigorously.…”

Section: Central Issues In Face Perception the Face-specificity Hypotmentioning

confidence: 96%

“…Multiple face-selective areas are present in the fusiform gyrus ( Jonas et al 2015, Weiner & Grill-Spector 2012. In our framework, these areas receive input not only from the OFA but also from early visual areas (Steeves et al 2006), beginning approximately 100 ms after stimulus onset (Parvizi et al 2012) and showing maximum face-selectivity approximately 170 ms after onset (Sadeh et al 2010).…”

Section: Ventral Stream Face-selective Areasmentioning

confidence: 99%

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A Revised Neural Framework for Face Processing

Duchaine

Yovel

2015

Annu. Rev. Vis. Sci.

398

392

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Face perception relies on computations carried out in face-selective cortical areas. These areas have been intensively investigated for two decades, and this work has been guided by an influential neural model suggested by Haxby and colleagues in 2000. Here, we review new findings about face-selective areas that suggest the need for modifications and additions to the Haxby model. We suggest a revised framework based on (a) evidence for multiple routes from early visual areas into the face-processing system, (b) information about the temporal characteristics of these areas, (c) indications that the fusiform face area contributes to the perception of changeable aspects of faces, (d) the greatly elevated responses to dynamic compared with static faces in dorsal face-selective brain areas, and (e) the identification of three new anterior face-selective areas. Together, these findings lead us to suggest that face perception depends on two separate pathways: a ventral stream that represents form information and a dorsal stream driven by motion and form information.

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“…Previous studies showed that face perception is disrupted specifically by stimulating the right inferior occipital gyrus (Jonas et al, 2012) as well as stimulating the right but not the left fusiform gyrus (Jonas et al, 2015; Parvizi et al, 2012), corresponding to the well-known prevalence of right hemispheric posterior lesions in causing prosopagnosia (Bouvier and Engel, 2006) and of larger responses to faces in the right hemisphere. However, Vinitha Rangarajan and Josef Parvizi show evidence in this issue from two rare patients whose face perception was distorted by stimulating the left fusiform cortex, which they attribute to the patients’ right hemispheric language dominance and left-handedness.…”

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confidence: 99%