Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits

Smiljanic, Sandra; Messaraa, Cyril; Lafon-Kolb, Virginie; Hrapovic, Nina; Amini, Nahid; Osterlund, Christina; Visdal-Johnsen, Lene

doi:10.3390/ijms232012507

Cited by 3 publications

(1 citation statement)

References 33 publications

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“…Birch juice, a colorless and transparent or can be slightly yellow fresh juice from the birch, contains rich nutrients and biologically active material. It is often regarded as a kind of simple and quick beverage, and it also has medicinal and cosmetic effects [10][11][12][13][14]. To date, birch juice contains 11 kinds of fatty acids, 18 kinds of amino acids, 4 kinds of vitamins and 18 kinds of mineral elements as well as compounds of nicotinic acid, essential oil, betula bud acid, saponin, cell division elements, growth elements, sulfur ammonia elements, and pyridoxine [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Clinical study of a spray containing birch juice for repairing sensitive skin

Shu

Zhao²,

Huo

et al. 2023

Arch Dermatol Res

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Sensitive skin is described as an unpleasant sensory response to a stimulus that should not cause a sensation. Sensitive skin affects an increasing proportion of the population. Sixty-seven participants who tested positive to lactic acid sting test were recruited and randomized into two groups to observe the clinical efficacy and safety of a new birch juice spray for repairing sensitive skin. One group used test spray A, while the other group used spray B as a control. Both groups were sprayed six times daily for 28 days. Noninvasive testing instruments were used to measure stratum corneum hydration, sebum content, transepidermal water loss rates, skin blood perfusion and current perception threshold before and after using spray. Facial images were captured by VISIA-CR, and the image analysis program (Image‐Pro Plus) was used to analyze these to obtain the redness value of the facial skin. Moreover, lactic acid sting test scores and participants’ self-assessments were also performed at baseline, week 2 and week 4. Both sprays A and B significantly decreased the lactic acid sting test score, transepidermal water loss rates, skin blood perfusion, and redness, while increasing the stratum corneum hydration. Compared to spray B, spray A increased sensory nerve thresholds at 5 Hz and decreased the transepidermal water loss rates, skin blood perfusion, and lactic acid sting test score. Sprays containing birch juice improved cutaneous biophysical properties in participants with sensitive skin.

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Section: Introductionmentioning

confidence: 99%

Clinical study of a spray containing birch juice for repairing sensitive skin

Shu

Zhao²,

Huo

et al. 2023

Arch Dermatol Res

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Antioxidative and Antimicrobial Evaluation of Bark Extracts from Common European Trees in Light of Dermal Applications

et al. 2023

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Plant species have developed effective defense strategies for colonizing diverse habitats and protecting themselves from numerous attacks from a wide range of organisms, including insects, vertebrates, fungi, and bacteria. The bark of trees in particular constitutes a number of components that protect against unwanted intruders. This review focuses on the antioxidative, dermal immunomodulatory, and antimicrobial properties of bark extracts from European common temperate trees in light of various skin pathogens, wound healing, and the maintenance of skin health. The sustainability aspect, achieved by utilizing the bark, which is considered a byproduct in the forest industry, is addressed, as are various extraction methods applied to retrieve extracts from bark.

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In Vitro Toxicity Evaluation of Some Plant Extracts and Their Potential Application in Xerosis cutis

Ghica,

Tănase,

Niculițe

et al. 2024

Cosmetics

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Xerosis cutis represents one of the most common dermatological diagnoses, which, when untreated, can be the trigger for open wounds, infections, and other skin diseases. Plant extracts are a valuable option for long-term treatments for xerosis due to their phytocompounds, especially polyphenols, flavonoids, triterpenes, and polysaccharides, with antioxidant, anti-inflammatory, antimicrobial, moisturizing, and reparatory effects. Active substances have different mechanisms; therefore, evaluating the effects on the cells can be a key indicator, providing valuable information in terms of both cytotoxicity and efficacy. The in vitro and in vivo toxicity tests performed for Betulae extractum, Liquiritiae extractum, and Avenae extractum highlighted potential toxic effects at higher concentrations in a dose-dependent relationship, but at lower levels they can be considered safe (12.5 µg/mL for birch and licorice extracts, 50 µg/mL for oat extract). Concerning the re-epithelialization process, the results revealed that all three dry extracts effectively stimulate skin cell migration, highlighting a potential anti-inflammatory effect by increasing the cell migration rate in conditions of induced inflammation associated with oxidative stress. Among the tested concentrations with a potential contribution to wound healing, the following standout: are birch bark extract 3 μg/mL, licorice root extract 7.5 µg/mL, and oat herb (harvested before flowering) extract 7.5 µg/mL.

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Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits

Cited by 3 publications

References 33 publications

Clinical study of a spray containing birch juice for repairing sensitive skin

Clinical study of a spray containing birch juice for repairing sensitive skin

Antioxidative and Antimicrobial Evaluation of Bark Extracts from Common European Trees in Light of Dermal Applications

In Vitro Toxicity Evaluation of Some Plant Extracts and Their Potential Application in Xerosis cutis

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