Betel nut use and hyperglycemia

Nabrinsky, Edward; Hasan, Badar; Asif, Talal; Pauly, Rebecca

doi:10.18590/mjm.2017.vol3.iss3.3

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…[ 11 , 32 ] It is common in South East Asia [ 3 ] and its major alkaloid is believed to interfere with insulin-induced glucose uptake. [ 14 ] Medical expenditure included the total amount [in American Dollars (US$)] of each disbursement (inpatient and outpatient care service) in 2013. The total annual costs were calculated by finding the sum of all outpatient and inpatient services and medical prescriptions.…”

Section: Methodsmentioning

confidence: 99%

Physical activity is associated with lower health care costs among Taiwanese individuals with diabetes mellitus

Wang²,

et al. 2020

Medicine

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The economic burden of diabetes has increased over time with disease severity. Previous publications investigating the effects of physical activity (PA) on medical costs have made use of small sample sizes. We assessed the relationship between PA and 1-year medical expenditure among Taiwanese patients with type-2 diabetes mellitus (T2DM). Data were recruited from three governmental databases, including the 2012 adult preventive health service database. Participants were grouped as inactive (no exercise), insufficiently active (exercise < 150 minutes/week), and sufficiently active (exercise >150 minutes/week) individuals. Patients were stratified according to age and Charlson score. Multivariate linear regression models were used to determine β-coefficients and their P values. Overall, 218,960 individuals were identified with diabetes. The prevalence of the disease was 13.1% among sufficiently active, 35% among insufficiently active, and 51.9% among physically inactive adults. In general, patients who had exercise >150 minutes/week had lower health care spending (i.e., US$ 755.83) followed by those who had less than 150 minutes/week (US$ 880.08) when compared with inactive patients ( P < .0001). Moreover, health care costs derived from outpatient or inpatient care were lower for sufficiently active than inactive participants ( P < .0001). Compared with being sedentary, PA was associated with lower health care costs of Taiwanese adults with diabetes mellitus.

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Section: Methodsmentioning

confidence: 99%

Physical activity is associated with lower health care costs among Taiwanese individuals with diabetes mellitus

Wang²,

et al. 2020

Medicine

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Antidiabetic effect and glucose tolerance of areca nut (Areca catechu) seed ethanol extract on alloxan-induced diabetic male rats

Musdja

Nurdin

Musir

2020

IOP Conf. Ser.: Earth Environ. Sci.

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Areca catechu fruit (Areca nut) is one component of betel chewing. There is an assumption that the antidiabetic effect of chewing betel is sourced from areca nut. This study aims to determine the anti-hyperglycemic effect and glucose tolerance of ethanol extract of areca nut (Areca catechu) seed in diabetic rats. Old Areca nut fruit was obtained from a garden in the Depok region, the suburb of Jakarta. Areca nut seeds were made into a fine powder, then macerated by using 70% ethanol at room temperature based on the Harbone method. Male rats were eligible for the trial; after acclimatization, rats were made diabetic by using alloxan. The rats for this trial were divided into 6 groups. Each of groups consisted of 5 rats. Glibenclamide was used as a positive control for anti-diabetic, and acarbose was used for glucose tolerance test, as normal control was given distilled water, while negative control was used 1% CMC Na, namely a solution suspending agent for test preparation. Areca nut seed extract was given with 3 types of doses, namely low, medium and high doses, namely 22.5 mg; 45 mg and 180 mg per 200 gr body weight (BW) rats, respectively. For measure blood, sugar levels were used as a glucometer tool. The result of this study showed that on 14 days of given test preparation, the statistical results with ANOVA test and Kruskal-Wallis test showed that medium doses of areca nut seed extract had the same anti-diabetic effect and glucose tolerance with positive control and were significantly different to negative controls. (P≤0.05). While on the low and high dose was not significantly different from negative controls (P≥0.05). Conclusion of this study, areca nut seed was very potential for antidiabetic and glucose tolerance.

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Betel nut use and hyperglycemia

Cited by 2 publications

References 5 publications

Physical activity is associated with lower health care costs among Taiwanese individuals with diabetes mellitus

Physical activity is associated with lower health care costs among Taiwanese individuals with diabetes mellitus

Antidiabetic effect and glucose tolerance of areca nut (Areca catechu) seed ethanol extract on alloxan-induced diabetic male rats

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