Bestimmung der stellung von O-substituenten bei 1,8-dihydroxy-anthrachinon-derivaten mit hilfe der NMR-spektroskopie

Rapid and Simple Biological Activity Screening of Some Rumex Species; Evaluation of Bioguided Fractions of R. scutatus and Pure Compounds

“…The bioguided fractionation of the R. scutatus led to the isolation of 4 anthraquinone aglycones which were iden tified by TLC, HPLC (Fig. 3) and spectroscopic analysis and comparison of these data with those previously reported (Demirezer, 1991;Miething, 1984;Labadie, 1971;Steglich and Lösel, 1969;Rauwald, 1981;Van Den Berg et al, 1988) and our Aloe emodin has already been reported as anti leukemic (Wei et al, 1992), chrysophanol, phys cion, emodin as cytotoxic against human hepa toma PLC/PRF/5 and KB cells. As far as we know our study is the first report for their toxicity against brine shrimp.…”

“…Standard Samples: Aloe-emodin, emodin, chrysophanol, physcion were isolated by us and comparison of these data with those previously re ported (Demirezer, 1991;Labadie, 1971;Miething, 1984;Rauwald, 1983;Steglich and Lösel, 1969). A solution of 3 mg aloe-emodin, emodin, chrysopha nol, physcion in 10 ml m ethanol was prepared as described in the sample preparation section.…”

Synthesen von Emodinaldehyd [1] / Synthesis of Emodine Aldehyde [1]

“…Lit. [20]) zur Ermittlung des Substituentenmusters heranzuziehen. Im vorliegenden Fall lassen sich die chemischen Verschiebungen der aromatischen Protonen 2-, 4-, 5-und 7-H der Komponente 10, von denen 5-und 7-H mit 7(5,7) ~ 2,5 Hz als saubere Dubletts erscheinen und 2-sowie 4-H mit 7(2,4) ~ 1,6 Hz wegen der Fernkopplungen zu den Protonen im Substituenten an C-3 breitere Signale aufweisen, mit denen ihrer unblockierten Stammverbindungen, dem Citreorosein 11 [21,22] …”

Antioxidant phenolic constituents from Fagopyrum dibotrys

“…The crude extract was further fractionated and purified over Diaion HP 20SS, Sephadex LH-20, Chromatorex ODS, MCI-gel CHP-20P and silica gel to give two new compounds 1 and 2, as well as 14 known compounds (3-16). The known ones were identified as lapathoside A (3) (Takasaki et al, 2001), quercetin (4) (Wenkert and Gottlieb, 1977), 3-methylquercetin (5) (Bacon et al, 1978), 3,5-dimethylquercetin (6), rutin (7) (Wenkert and Gottlieb, 1977), emodin-8-O-␤-d-glucopyranoside (8) (Steglich and Losel, 1969), gallic acid (9), 6-O-galloyl-d-glucose (10) (Nonaka and Nishioka, 1983), (+)-catechin (11) (Nonaka et al, 1983a), (−)-epicatechin (12) (Nonaka and Nishioka, 1982), procyanidin B-1 (13) (Nonaka et al, 1981), procyanidin B-2 (14) (Nonaka et al, 1981), 3,3 -di-O-galloyl-procyanidin B-2 (15) (Nonaka et al, 1981) and 3 -O-galloyl-procyanidin B-2 (16) (Nonaka et al, 1983b) by the spectroscopic evidences and comparing with literature data (Fig. 1).…”