Best Practice Statement on Cryosurgery for the Treatment of Localized Prostate Cancer

Babaian, R. Joseph; Donnelly, Bryan J.; Bahn, Duke; Baust, John G.; Dineen, Martin; Ellis, D. S.; Katz, Aaron E.; Pisters, Louis L.; Rukstalis, Daniel B.; Shinohara, Katsuto; Thrasher, J. Brantley

doi:10.1016/j.juro.2008.07.108

Cited by 220 publications

(215 citation statements)

References 90 publications

Supporting

Mentioning

208

Contrasting

Unclassified

Order By: Relevance

“…Cryosurgery is appropriate for men who either do not want or who are not good candidates for more invasive therapies due to comorbidities [Babaian et al 2008]. Primary TFT is an option for men with organ confined disease (up to cT2b), any Gleason Grade, with a negative metastatic evaluation [Crawford and Barqawi, 2007;Babaian et al 2008].…”

Section: Patient Selection For Tftmentioning

confidence: 99%

“…Other characteristics that need to be considered are tumor burden, which can be accurately determined from the mapping biopsies and Gleason Grade [Crawford and Barqawi, 2007]. The Best Practice Statement on Cryosurgery released in 2008 indicated that subtotal cryosurgery or hemiablation needs further evaluation in order to make a recommendation about its usefulness as a treatment type for prostate cancer [Babaian et al 2008]. Also, strict patient selection criteria have not been determined for the hemiablation technique; however, it may be used for patients who are active surveillance candidates with organ-confined unilateral disease but would prefer some form of therapy [Babaian et al 2008].…”

Section: Patient Selection For Tftmentioning

confidence: 99%

“…Other possible indications for cryotherapy include patients who need salvage therapy following radiation therapy or failed cryotherapy [Barzell et al 2003]. Additionally, select individuals who have a narrow pelvis and cannot tolerate electron beam radiation therapy, persons who have had previous pelvic radiation, persons with irritable bowel disease, or those with rectal disorders may be good candidates for cryotherapy [Babaian et al 2008]. …”

Section: Patient Selection For Tftmentioning

confidence: 99%

“…The active thaw step of cryotherapy affects only the tissue next to the cryoprobe. The tissue at the edge of the ice ball around the cryoprobe will still thaw passively [Babaian et al 2008]. Lastly, two cycles of freezing and thawing have shown increased effectiveness in destroying tissue compared to a single cycle [Babaian et al 2008;Han and Belldegrun, 2004].…”

Section: Mechanism Of Action Of Cryotherapymentioning

confidence: 99%

“…They include include PSA <0.4 ng/ml, <0.5 mg/ml, and <1.0 ng/ml; 3 consecutive PSA increases; or nadir plus 2.0 ng/ml [Babaian et al 2008]. The multiple definitions of 'disease free' make patient follow-up and comparison of different treatment types very difficult.…”

Section: Mechanism Of Action Of Cryotherapymentioning

confidence: 99%

See 4 more Smart Citations

Targeted focal therapy for prostate cancer: a review of the literature

Sullivan

Crawford

2009

Therapeutic Advances in Urology

View full text Add to dashboard Cite

Improvements in prostate cancer diagnosis and treatment have resulted in a decreasing age-adjusted death rate. But improved diagnostic tools have not delivered a proportionate decrease in mortality, primarily because physicians now are diagnosing and treating more clinically insignificant tumors. Targeted focal therapy (TFT) uses three dimensional (3D) mapping biopsies to guide cryotherapy so that it targets lesions themselves while sparing surrounding healthy tissues, thereby avoiding side effects associated with more invasive treatments. As such, TFT can provide a bridge between active surveillance and more aggressive treatments for patients with low-risk tumors. It is appropriate for men who either do not want or are not good candidates for more aggressive therapies. Identifying patients who are appropriate candidates for TFT is challenging, but the mapping biopsy technique helps identify individuals who have localized disease and could benefit from this treatment. In recent years, improvements in cryotherapy have increased its efficacy while decreasing complications. At the present time using cryotherapy to target and destroy the cancer(s) is appealing. Other approaches to less aggressive therapies are discussed including gland hemi ablation, high intensity ultrasound (HIFU) and others. Going forward, patients will benefit further from development of better imaging technologies and completion of long-term survival studies.

show abstract

Section: Patient Selection For Tftmentioning

confidence: 99%

Section: Patient Selection For Tftmentioning

confidence: 99%

Section: Patient Selection For Tftmentioning

confidence: 99%

Section: Mechanism Of Action Of Cryotherapymentioning

confidence: 99%

Section: Mechanism Of Action Of Cryotherapymentioning

confidence: 99%

See 3 more Smart Citations

Targeted focal therapy for prostate cancer: a review of the literature

Sullivan

Crawford

2009

Therapeutic Advances in Urology

View full text Add to dashboard Cite

show abstract

Primary cryotherapy for localised or locally advanced prostate cancer

Jung

Goldfarb

Reddy

et al. 2018

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

BackgroundTraditionally, radical prostatectomy and radiotherapy with or without androgen deprivation therapy have been the main treatment options to attempt to cure men with localised or locally advanced prostate cancer. Cryotherapy is an alternative option for treatment of prostate cancer that involves freezing of the whole prostate (whole gland therapy) or only the cancer (focal therapy), but it is unclear how effective this is in comparison to other treatments. ObjectivesTo assess the effects of cryotherapy (whole gland or focal) compared with other interventions for primary treatment of clinically localised (cT1-T2) or locally-advanced (cT3) non-metastatic prostate cancer. Search methodsWe updated a previously published Cochrane Review by performing a comprehensive search of multiple databases (CENTRAL, MEDLINE, EMBASE), clinical trial registries (ClinicalTrials.gov, World Health Organization International Clinical Trials Registry Platform) and a grey literature repository (Grey Literature Report) up to 6 March 2018. We also searched the reference lists of other relevant publications and conference proceedings. We applied no language restrictions. Selection criteriaWe included randomised or quasi-randomised trials comparing cryotherapy to other interventions for the primary treatment of prostate cancer. Data collection and analysisTwo independent reviewers screened the literature, extracted data, and assessed risk of bias. We performed statistical analyses using a random-effects model and interpreted them according to the Cochrane Handbook for Systematic Reviews of Interventions. We rated the quality of evidence (QoE) according to the GRADE approach.

show abstract

Ultrashort TE Imaging of Cryotherapy

Daniel

Pauly

2012

Encyclopedia of Magnetic Resonance

View full text Add to dashboard Cite

Best Practice Statement on Cryosurgery for the Treatment of Localized Prostate Cancer

Cited by 220 publications

References 90 publications

Targeted focal therapy for prostate cancer: a review of the literature

Targeted focal therapy for prostate cancer: a review of the literature

Primary cryotherapy for localised or locally advanced prostate cancer

Ultrashort TE Imaging of Cryotherapy

Contact Info

Product

Resources

About