Best Cases from the AFIP

Hopkins, John K.; Giles, Henry; Wyatt-Ashmead, Josephine; Bigler, Steven A.

doi:10.1148/rg.242035070

Cited by 29 publications

(6 citation statements)

References 13 publications

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“…Histology Cystic renal tumors in children are real diagnostic challenges as CN, CPDN and CWT are difficult to distinguish on radiology [1,2] . Discrimination between these subtypes is only possible by histology.…”

Section: Discussionmentioning

confidence: 99%

Cystic Nephroma, Cystic Partially Differentiated Nephroblastoma and Cystic Wilms’ Tumor in Children: A Spectrum with Therapeutic Dilemmas

Hoek¹,

Krijger²,

Ven

et al. 2009

Urol Int

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Background: Cystic renal tumors are a diagnostic and therapeutic challenge. Cystic nephroma (CN), cystic partially differentiated nephroblastoma (CPDN) and cystic Wilms’ tumor (CWT) are a spectrum with CN at the benign end, CWT at the malignant end and CPDN in the intermediate position. CN and stage 1 CPDN are often treated with surgery alone. International Society of Pediatric Oncology (SIOP) protocols for Wilms’ tumor (WT) advocate preoperative chemotherapy, which may be unnecessary and potentially harmful in CN and in stage 1 CPDN. There are difficulties in differentiating the three types using imaging techniques. Therefore, controversies exist regarding the optimal treatment. Methods: We describe 6 children, who each had a postoperative diagnosis of CN, CPDN or CWT, and we retrospectively evaluate the treatment strategies. Results: The three types cannot be differentiated using imaging techniques, although the presence of solid components in the tumor is indicative of WT. Conclusions: Surgery as first-line therapy should be seriously considered in children who have a cystic renal tumor, but further collaborative studies are needed since the distinction line between CPDN and CWT is not always clear.

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Section: Discussionmentioning

confidence: 99%

Cystic Nephroma, Cystic Partially Differentiated Nephroblastoma and Cystic Wilms’ Tumor in Children: A Spectrum with Therapeutic Dilemmas

Hoek¹,

Krijger²,

Ven

et al. 2009

Urol Int

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“…Pre-operative biopsy is controversial with some authors arguing that if the diagnosis can be confirmed, observation may be an option, 12 as only a single case of malignant transformation has been reported. 17 This may be a consideration, however, we as well as others 9,10,13,14,18 would favor resection in the presence of symptoms, increasing size, or uncertain diagnosis. Most cases have historically been treated with nephrectomy.…”

Section: Discussionmentioning

confidence: 98%

“…The septa may enhance with gadolinium administration. 13,14 Despite these characteristics, definitive radiologic diagnosis is impaired by the rarity of the lesion as well as its similarities to other cystic lesions.…”

Section: Discussionmentioning

confidence: 99%

Case report: a left upper quadrant complex cystic mass

Choi

Mirani²,

Kim

2012

International Journal of Surgery Case Reports

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A 61-year-old woman presented with left upper quadrant/flank pain and increasing abdominal girth. CT scan showed a large complex, multi-cystic lesion in the left abdomen. Laparotomy revealed a large retroperitoneal mass attached to the left kidney. Left nephrectomy was performed and pathology demonstrated a benign cystic nephroma. Surgical oncologists should be aware of this rare renal lesion as the clinical and radiographic presentation may mimic other intra-abdominal cystic lesions.

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“…5 Diagnosis is confirmed by USG or CT. 6 Surgical Excision is treatment of choice. 7 PPB is a very rare tumor. Previously it was also know as cystic rhabdomyosarcoma, pulmonary blastoma of childhood etc.…”

Section: Discussionmentioning

confidence: 99%