Berichtsqualität systematischer Reviews und Metaanalysen: PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses)

Walther, Stefan; Schuetz, Georg M.; Hamm, Bruna Laís; Dewey, Marc

doi:10.1055/s-0031-1281809

Cited by 17 publications

(11 citation statements)

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“…The meta-analysis was conducted according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines [9]. …”

Section: Methodsmentioning

confidence: 99%

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

Liu

2017

BMC Cardiovasc Disord

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BackgroundThe therapeutic efficacy of coenzyme Q10 on patients with cardiac failure remains controversial. We pooled previous clinical studies to re-evaluate the efficacy of coenzyme Q10 in patients with cardiac failure.MethodsWe searched PubMed, Cochrane Library, EMBASE, and Clinical Trials.gov databases for controlled trials. The endpoints were death, left heart ejection fraction, exercise capacity, and New York Heart Association (NYHA) cardiac function classification after treatment. The pooled risk ratios (RRs) and standardized mean difference (SMD) were used to assess the efficacy of coenzyme Q10.ResultsA total of 14 RCTs with 2149 patients met the inclusion criteria and were included in the analysis. Coenzyme Q10 decreased the mortality compared with placebo (RR = 0.69; 95% CI = 0.50–0.95; P = 0.02; I 2 = 0%). A greater improvement in exercise capacity was established in patients who used coenzyme Q10 than in those who used placebo (SMD = 0.62; 95% CI = 0.02–0.30; P = 0.04; I 2 = 54%). No significant difference was observed in the endpoints of left heart ejection fraction between patients who received coenzyme Q10 and the patients in whom placebo was administered (SMD = 0.62; 95% CI = 0.02–1.12; P = 0.04; I 2 = 75%). The two types of treatment resulted in obtaining similar NYHA classification results (SMD = −0.70; 95% CI = −1.92–0.51; P = 0.26; I 2 = 89%).ConclusionPatients with heart failure who used coenzyme Q10 had lower mortality and a higher exercise capacity improvement than the placebo-treated patients with heart failure. No significant differences between the efficacy of the administration of coenzyme Q10 and placebo in the endpoints of left heart ejection fraction and NYHA classification were observed.Electronic supplementary materialThe online version of this article (doi:10.1186/s12872-017-0628-9) contains supplementary material, which is available to authorized users.

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“…The meta-analysis was conducted according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines [9]. …”

Section: Methodsmentioning

confidence: 99%

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

Liu

2017

BMC Cardiovasc Disord

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“…The meta-analysis was complied with Preferred Reporting Items For Systematic Review and Meta-analysis (PRISMA). [9] As it is a meta-analysis study, ethical approval and informed consent are not required.…”

Section: Methodsmentioning

confidence: 99%

Efficacy and safety of bivalirudin versus heparin in patients with diabetes mellitus undergoing percutaneous coronary intervention

Zhang

Yang²

2017

Medicine

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“…We (H.L., Y.X., N.Y., and W.Y.) conducted the meta-analysis according to Preferred Reporting Items for Systematic Review and Meta-analysis [6] and Cochrane Handbook for Systematic Reviews of Interventions guidelines.…”

Section: Methodsmentioning

confidence: 99%

Efficacy and Safety of Hyaluronic Acid Gel for the Prevention of Intrauterine Adhesion: A Meta-Analysis of Randomized Clinical Trials

Liu

et al. 2018

Gynecol Obstet Invest

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Background: The aim of this study is to assess the clinical effectiveness and safety of hyaluronic acid gel for the prevention of postoperative intrauterine adhesions (IUAs). Methods: PubMed, Cochrane Library, Embase and ClinicalTrials.gov databases were searched for randomized controlled trials. Results: Six RCTs with a total of 564 patients met the inclusion criteria. The meta-analysis showed that, compared to no other treatment method, hyaluronic acid gel significantly reduced the rate of any IUA (risk ratio [RR] 0.68; 95% CI 0.53–0.86; p = 0.03; I² = 64%) and adhesion score (standard mean difference = –2.90; 95% CI –4.61 to –1.49; p < 0.00001; I² = 98%) following intraperitoneal or intrauterine surgery. Treatment lowered the rate of IUAs classified as moderate (RR 0.26; 95% CI 0.13–0.52; p = 0.13; I² = 0%), but not those deemed mild (RR 0.86; 95% CI 0.62–1.21; p = 0.39; I² = 3%) or severe (RR 0.33; 95% CI 0.03–3.09; p = 0.33; I² = 0). Compliance with hyaluronic acid gel treatment was low. Conclusion: Hyaluronic acid gel can prevent IUAs, particularly those with moderate severity and a lower adhesion score.

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Berichtsqualität systematischer Reviews und Metaanalysen: PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses)

Cited by 17 publications

References 0 publications

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

Efficacy and safety of bivalirudin versus heparin in patients with diabetes mellitus undergoing percutaneous coronary intervention

Efficacy and Safety of Hyaluronic Acid Gel for the Prevention of Intrauterine Adhesion: A Meta-Analysis of Randomized Clinical Trials

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