“…The role of catecholamines in the pathogenesis of hypertension remains largely unknown. Studies of the urinary excretion of catecholamines and their metabolites in human essential hypertension have yielded confiicting results, showing raised (Ritzel andHunzinger, 1963), lowered (Brunjes, 1964), or normal (Crout, Pisano andSjoerdsma, 1961) levels. Manger, Wakim andBollman (1959) found no difference in the plasma levels of catecholamines in hypertensive patients and normal subjects.…”