Benzopyrans from Melicope ptelefolia leaves

Kamperdick, Christine; Van, Nguyen Hong; Sung, Trần Văn; Adam, Günter

doi:10.1016/s0031-9422(97)00059-9

Cited by 40 publications

(27 citation statements)

References 7 publications

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“…An IR spectrum of 13 showed absorption bands at 3781 and 1730 cm À1 , which corresponded to hydroxy and carbonyl groups, respectively. The 1 H and 13 C NMR data showed typical patterns of a chromenetype compound (Kamperdick et al, 1997) and exhibited peaks resembling those of leptonol (Li and Zhu, 1998). However, the arrangement of functional groups in the aromatic ring of 13 appeared to be different from those of reported compounds.…”

Section: Resultsmentioning

confidence: 86%

“…In Vietnamese traditional medicine, the extract prepared from M. pteleifolia, under the local name of "Ba chac", is empirically used for the treatment of high fevers, colds and various inflammatory conditions. Previous phytochemical investigations established that the main constituents of this plant were benzopyrans (Guo-Lin et al, 1997;Kamperdick et al, 1997), furoquinoline alkaloids (Sichaem et al, 2014) and glycosidic compounds (Zhang et al, 2012). It was also found that the methanol extract from its leaves and twigs exhibited anti-inflammatory activities through either 5-lipoxygenase (5-LOX) inhibition (Shaari et al, 2011) or interactions with Syk/Src targets (Yoon et al, 2013), which are ethnopharmacologically relevant for its traditional usage.…”

Section: Introductionmentioning

confidence: 94%

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Chemical constituents from Melicope pteleifolia leaves

Nguyen

Choi

et al. 2016

Phytochemistry

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Section: Resultsmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 94%

Chemical constituents from Melicope pteleifolia leaves

Nguyen

Choi

et al. 2016

Phytochemistry

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“…A few sesquiterpenes were identified by comparison of their spectral data (MS, 13 12,34 (114, 0.3%). The MS spectrum of β-curcumene (67) was identical to that reported in the literature.…”

Section: Detailed Analysis Of Sample Amentioning

confidence: 99%

Composition and chemical variability of the bark oil of Cedrelopsis grevei H. Baillon from Madagascar

Cavalli

Tomi

Bernardini

et al. 2003

Flavour & Fragrance J

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A commercial sample of Cedrelopsis grevei H. Baillon from Madagascar was repeatedly chromatographed and the combined analysis of all the fractions by GC, GC-MS and 13 C-NMR led to the identification of 114 components. The major constituents were (E)-β-caryophyllene (9.3%), α-copaene (7.7%), α-selinene (5.8%), δ-cadinene (4.9%), β-selinene (4.5%), α-humulene (3.3%) and β-bisabolene (2.8%). Analysis of five other commercial samples confirmed the pre-eminence of sesquiterpene hydrocarbons and exhibited a variation in the contents of the main components: ishwarane (1.0-17.4%), (E)-β-caryophyllene (1.3-12.5%), α-copaene (4.9-11.0%), β-elemene (0.2-9.6%) and α-selinene (1.1-9.4%).

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“…The leaf of the plant has been reported to show fungicidal (Kumar, Karunaratne, Sanath, Meegalle, & Macleod, 1990), antioxidant and nitric oxide inhibitory activities (Abas, Lajis, Israf, Khozirah, & Umi Kalsom, 2006), while its aerial parts shown antibacterial (Manandhar, Hussaini, Kapil, & Shoeb, 1985;Rasadah & Zakaria, 1988). Phytochemical studies on the leaves of the species collected from Sri Lanka revealed the presence of furoquinone alkaloids and acetophenones (Kumar et al, 1990), while the leaves collected in Vietnam were shown to contain benzopyrans as major constituents (Kamperdick, Van, Sung, & Adam, 1997;Nguyen, Kamperdick, Tran, & Adam, 1998). Our own studies on the leaves of the plant growing in Malaysia, reported the presence of p-O-geranylcoumaric acid as a major constituent and several polyprenylated acetophenones and benzylisoquinoline alkaloids (Abas et al, 2010;Shaari, Safri, Abas, Lajis, & Israf, 2006).…”

Section: Introductionmentioning

confidence: 99%

Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis

et al. 2011

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a b s t r a c tThe 'Ulam', a traditional Malay dish, are plants that can be eaten raw, as a form of local salad. The shoots and young leaves of Melicope ptelefolia are among the popular species, believed to be high in nutritional and medicinal values. The metabolomic fingerprinting analysis of the ethanolic extracts of leaves of M. ptelefolia was carried out using 1 H Nuclear Magnetic Resonance (NMR) spectroscopy and multivariate data analysis in order to differentiate young and mature leaves and to evaluate the variation of their chemical composition. Principle component analysis (PCA) of the 1 H NMR spectra showed a clear discrimination between the young and mature leaves extracts by PC3 and PC4. The compounds responsible for the differentiation were identified by comparison of 1 H NMR chemical shifts and qualitative HPLC. The young leaves were found to be richer in fatty acids and the levels of the three marker compounds, p-Ogeranylcoumaric acid, 2,4,6-trihydroxy-3-geranylacetophenone and 2,4,6-trihydroxy-3-prenylacetophenone, were clearly higher. The mature leaves contain higher levels of sugars and glycosidic components.

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Benzopyrans from Melicope ptelefolia leaves

Cited by 40 publications

References 7 publications

Chemical constituents from Melicope pteleifolia leaves

Chemical constituents from Melicope pteleifolia leaves

Composition and chemical variability of the bark oil of Cedrelopsis grevei H. Baillon from Madagascar

Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis

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