Benign uterine leiomioma with lung lesions

Abstract

Clinical cases of uterine leiomyoma with secondary lung involvement are described. The results of X-ray, computerized tomography, and histological examination of lung specimens, as well as those of heterozygosity and microsatellite instability are presented. Our own experience and the few descriptions available to date in the literature confirm the pseudo tumorous nature of benign uterine leiomyoma with lung involvement which should be considered as nodular dyshormonal hyperplasia. The signs of genetic instability ՛s identification do not allow to differentiate clearly between the benign or malignant nature of the disease. The key role in the differential diagnosis of uterine leiomyoma with lung involvement and leiomyosarcoma belongs to unprejudiced clinical observation.