Benign Pleomorphic Adenoma of the Larynx: Report of a Case and Review and Analysis of 20 Additional Cases in the Literature

Dubey, Siba P.; Banerjee, Satyabrata; Ghosh, L. M.; Roy, Sudipta

doi:10.1177/014556139707600811

Cited by 34 publications

(14 citation statements)

References 13 publications

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“…Most tumors commonly present as submucosal subglottic masses of which around 20 cases have been reported in literature. [3][4][5][6]…”

Section: Discussionmentioning

confidence: 99%

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Laser Resection of Subglottic Pleomorphic Adenoma

Nair¹,

Pai²,

Chaturvedi³

et al. 2010

International Journal of Head and Neck Surgery

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A 48 years old male was referred to our center, a specialized tertiary comprehensive cancer center with a history of progressively worsening dyspnea since 6 months. The patient was admitted in a general hospital for stridor and treated with steroids following which his stridor subsided. Further investigations with rigid laryngoscopy under general anesthesia revealed a subglottic mass. The biopsy was reported as pleomorphic adenoma and he was referred to us for further management.On presentation, the patient had no stridor or hoarseness. On flexible laryngoscopy, a pedunculated mass with a broad base was seen arising 1 cm below the level of the vocal cords, extending inferiorly for about 1 cm and occluding 30% of the subglottic lumen. Both the vocal cords were normal in appearance and mobility (Fig. 1). The rest of the tracheobronchial tree was normal. A computed tomography (CT) scan of the larynx revealed a lobulated mass in the subglottis arising from the posterior wall measuring 1.2 × 1.2 × 1.4 cm, extending anterior and abutting the right lateral wall of subglottis with no erosion of the underlying cartilage (Figs 2 and 3). The patient underwent endolaryngeal endoscopic CO 2 laser (Lumenis TM Israel, 3.5 W, superpulse mode) resection of the mass under general anesthesia using apnea technique. The base of the mass was completely resected with wide margins. The cricoid cartilage was not exposed. Postoperative recovery was uneventful.The histopathology report demonstrated a biphasic tumor in submucosa consisting of epithelial nests, trabeculae and tubules embedded in a fibromyxoid stroma (Fig. 4A). The epithelial component composed of 2 cell types: epithelial cells arranged in duct like structures or cords and myoepithelial cells situated at around the ducts and in solid Fig. 1: Flexible laryngoscopy picture showing presence of pedunculated mass arising from posterior wall of subglottis, compromising laryngeal lumen AbstractTumors arising from the minor salivary glands in the larynx are rare. The most common tumors occurring here are adenoid cystic carcinomas. 1 Among the benign tumors, pleomorphic adenoma is the most common. 1 We present a case of subglottic pleomorphic adenoma which was managed by endolaryngeal endoscopic CO 2 laser surgery. Laser as a primary treatment modality for the treatment of subglottic pleomorphic adenomas has not been well-described, as only one case has been reported in literature using this modality.

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“…Most tumors commonly present as submucosal subglottic masses of which around 20 cases have been reported in literature. [3][4][5][6]…”

Section: Discussionmentioning

confidence: 99%

“…A variety of approaches have been described in literature. Pharyngotomy 3,4 has been advocated especially for supraglottic lesions. Laryngofissure 5 has been used in patients with glottic or subglottic disease.…”

mentioning

confidence: 99%

Laser Resection of Subglottic Pleomorphic Adenoma

Nair¹,

Pai²,

Chaturvedi³

et al. 2010

International Journal of Head and Neck Surgery

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“…По данным литературы, плеоморфная аденома встречается также в органах дыхания [4][5][6][7]. При этом поражение опухолью гортани встречается очень редко [8,9]. В литературе описано 27 наблюдений плеоморфной аденомы гортани [10].…”

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“…Опухоль может возникать в любом отделе гортани, в основном встречались поражение надгортанника и подголосового отдела гортани [8,9,11,12].…”

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Laryngeal pleomorphic adenoma

Мустафаев¹

2017

Vestn. otorinolaringol.

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Pleomorphic adenomas are the most widespread epithelial tumours originating from the salivary glands. In almost 90% of the cases, they are localized in the parotid salivary glands. Pleomorphic adenomas only rarely affect the larynx. To the best of our knowledge, as many as 27 cases of laryngeal pleomorphic adenoma have thus far been described in the special literature. The present article was designed to report a case of pleomorphic adenoma in the larynx of a 76 year-old male patient. The surgical treatment of this condition proved beneficial for the patient whose condition remains uncomplicated by the relapse of the tumour during the 5 year-long postoperative follow-up.

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