Malignant mixed tumor of the larynx

Abstract

The lesion in this case was considered to be a malignant mixed tumor. Differences between this tumor and that of laryngeal chondrosarcoma are discussed.

True carcinosarcoma of the larynx

“…1 Regarding the larynx, the terms carcinosarcoma and malignant mixed tumour used in the literature might describe the same tumour. 7 Using the above criteria to make the diagnosis, we conclude that true carcinosarcoma of the larynx is extremely rare.…”

“…7,8 In our group, at the time of writing, two patients had suffered regional cervical lymph node metastasis and were still alive with disease after neck dissection, while one patient had died from distant metastasis. The prognosis of carcinosarcoma of the larynx seems to be worse than that of squamous cell laryngeal carcinoma, and metastasis to cervical lymph nodes seems to be more frequent.…”

Carcinosarcoma de laringe: Reporte de dos casos

“…En contraste, la denominación carcinosarcoma corresponde a un tumor bifásico con 2 componentes malignos distinguibles, en el cual solo el componente carcinomatoso es positivo para citoqueratina y el componente mesenquimático para vimentina y otros marcadores que dependen de la diferenciación expresada por el tumor 7,15 . En cuanto a la laringe, los términos carcinosarcoma y tumor maligno mixto utilizado en la literatura puede hacer referencia al mismo tipo de tumor en cuestión 16 . Se desprende de este análisis que el verdadero carcinosarcoma de laringe representa una entidad extremadamente rara con escasos reportes en la literatura occidental y sin casos reportados anteriormente en Latinoamérica.…”

Endoscopic CO(2) Laser Horizontal Partial Laryngectomy in Larynx Carcinosarcoma

“…According to the World Health Organization (WHO) classification [12], three different subtypes of malignant mixed tumours can be identified: carcinoma ex-pleomorphic adenoma, metastasizing mixed tumor, and carcinosarcoma [13, 14]. In carcinoma ex-pleomorphic adenoma, the epithelial component only becomes malignant (thus developing an adenocarcinoma), while in metastasizing mixed tumor and carcinosarcoma, or true malignant mixed tumor, there is a dual malignant component (carcinomatous and sarcomatous) which are therefore considered biphasic [15, 16].…”