Benign Fibrous Histiocytoma: Report of Case

Abstract

Benign fibrous histiocytoma is a rare and usually painless oral neoplasm found in adults that may affect either soft tissue or bone typically noted in their fifth decade. This case was found in a 32 year-old Caucasian male who presented with a fairly well circumscribed unilocular radiolucent lesion extending from the mandibular right first incisor to the left first premolar and reaching the inferior mandible on a panoramic radiograph. A bony window was created and the intrabony lesion was curetted. Multiple sections revealed a cellular tumor composed of uniform spindle-shaped cells arranged in a prominent whorled or storiform pattern. Scattered xanthoma cells, multinucleated giant cells, lymphocytes, and deposits of hemosiderin were noted throughout the lesional stroma. Although malignant fibrous histiocytoma of the bone is relatively well known, benign fibrous histiocytoma of the bone is very rare.

Multiple benign fibrous histiocytomas of the mandible: A case report and review of the literature

“…According to the results of the present review, the choice of surgical method for mandible BFH is mainly based on the size of the mass and also the general condition of the patient. Transoral curettage is suggested when the CBCT scan indicates that the maximum diameter of the BFH lesion is <5.0 cm, while segmental mandibulectomy is advisable when it exceeds 5.0 cm ( 7 , 9 , 13 ). However, Heo et al ( 9 ) performed segmental mandibulectomy for the tumor with a maximum diameter of <5.0 cm.…”

“…According to the 2020 World Health Organization (WHO) classification of tumors of bone, BFH is categorized into the same disease entity as non-ossifying fibroma (3). Most bony BFHs occur in the pelvic bone, femur and tibia, which share identical histological characteristics with cutaneous BFH (5)(6)(7)(8). However, mandibular involvement of BFH is rare and only 11 cases have been reported to date (5,7,(9)(10)(11)(12)(13)(14)(15)(16).…”

“…Most bony BFHs occur in the pelvic bone, femur and tibia, which share identical histological characteristics with cutaneous BFH (5)(6)(7)(8). However, mandibular involvement of BFH is rare and only 11 cases have been reported to date (5,7,(9)(10)(11)(12)(13)(14)(15)(16). The present study reported a case of mandibular multiple BFH treated at the Affiliated Hospital of Stomatology, Sun Yat-Sen University (Guangzhou, China), who was followed up for 46 months.…”

Benign fibrous histiocytoma: A rare case involving jaw bone

“…Among the eight mandibular BFH, five involved posterior region,[ 2 3 4 5 6 ] two involved condylar region[ 7 8 ] and one extended from mandibular right incisor to the left premolar region. [ 9 ] In all the cases, age ranged from 30 to 50 years, with no significant gender predilection. The most common complaints were pain or a long-standing swelling indicating a slow growing nature of this entity.…”

Benign fibrous histiocytoma of the mandible

“…We do not consider that their cases represent BFHs from the clinical, histological and radiographic features. Ertas and Buyukkurt (9) reported a case of BFH involving the mandible. It is difficult to evaluate this case adequately because of unconvincing photomicrograph.…”