Benign Chondroid Syringoma on Chin: A Case Report and Literature Review

Abstract

Chondroid syringoma is a cutaneous adnexal tumor originating from sweat glands origin. It is rare in occurrence and usually benign, having an incidence of 0.01 to 0.098%. As these tumors are uncommon, their diagnosis is missed many times and are misdiagnosed. Hence in any case of facial skin swelling increasing slowly in size, this entity should be kept in mind as one of the possibilities and differential diagnosis. Histopathological examination of the excision biopsy gives the definitive confirmatory diagnosis. Surgically excising the swelling locally along with a surrounding normal tissue cuff is the standard treatment given which prevents recurrence. Hereby we present a 35-year-old case of facial chondroid syringoma having a focal component of eccrine hidrocystoma, keratinous cyst as well as syringocystadenoma papilliferum on the chin that was clinically suspected to be an epidermoid cyst or mucocele.

Cutaneous Mixed Tumour: A Rare Presentation of a Scrotal Lump Mimicking an Accessory Testis

“…The characteristic histological features include epithelial elements comprising of cuboidal or polygonal cells forming nests, ductal structures and intercommunicating tubulo-alveolar structures admixed with myoepithelial cells in a chondromyxoid matrix and occasional keratinous cysts. Mesenchymal elements if present show osseous, chondroid and adipocytic differentiation [ 2 , 3 , 5 , 7 ]. On histochemical stains the chondromyxoid areas are positive for mucicarmine, periodic acid-Schiff (PAS) and Alcian Blue (AB), indicating it be acid mucopolysaccharides found in normal cartilage [ 4 , 7 ].…”

“…Treatment of CMT involves complete surgical excision with an appropriate margin of normal tissue [ 2 , 8 ]. This ensures the entire lesion is removed which is essential to reduce the risk of recurrence [ 1 , 5 , 8 , 10 , 11 ].…”

“…On palpation they usually feel firm and well-circumscribed [1,8]. Typically these tumours arise in the head and neck region [2][3][4]. Rare cases have been reported presenting in the skin of abdomen, axilla, penis, vulva, scrotum, hands and feet [5,7,9].…”

“…The diagnosis of CMT is usually not made on preoperative clinical or radiological findings. Histopathological analysis of the excised lesion remains the mainstay for the diagnosis of CMT [2,4,[9][10][11]. CMTs are mixed tumours with multiple components, and depending on the area sampled not all components may be represented in the excised material [2,9].…”

“…Cutaneous mixed tumour (CMT) is a rare benign mixed tumour of the skin composed of epithelial, myoepithelial and mesenchymal components with an incidence of less than 0.01% of all primary skin tumours [1]. CMTs most commonly occur in the head and neck region [1][2][3]. Genital regions are very rarely involved.…”