Benign chondroblastoma.A study of 125 cases

Dahlin, David C.; Ivins, John C.

doi:10.1002/1097-0142(197208)30:2<401::aid-cncr2820300216>3.0.co;2-b

Cited by 306 publications

(175 citation statements)

References 18 publications

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“…Chondroblastoma is an uncommon benign bone tumour, which is locally aggressive [1][2][3][4], and arises from a secondary ossification centre in epiphyseal plates and apophyses [5][6][7]. Chondroblastoma accounts for approximately 1-2 % of all primary bone tumours [8].…”

Section: Introductionmentioning

confidence: 99%

“…Chondroblastoma accounts for approximately 1-2 % of all primary bone tumours [8]. It usually occurs in adolescents and young adults [2,9], whereby males predominate with a ratio of 3 to 2 [3,10]. It commonly involves the tibia, femur, and humerus [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…It usually occurs in adolescents and young adults [2,9], whereby males predominate with a ratio of 3 to 2 [3,10]. It commonly involves the tibia, femur, and humerus [2,3]. Flat bones are involved in about 10 % of cases [11].…”

Section: Introductionmentioning

confidence: 99%

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Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Mashhour

Rahman

2013

International Orthopaedics (SICOT)

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Purpose Various methods for the treatment of chondroblastoma of bone have been used including simple curettage, or combined with bone grafting, in addition to the use of adjuvant therapy. However, local recurrence still represents a challenge in the management of this aggressive tumour. This study focuses on evaluating the role of intraregional extended curettage together with the use of adjuvant cryotherapy and autogenous bone grafting in the treatment of benign chondroblastoma of bone aiming to decrease the recurrence rate. Methods All patients with chondroblastoma included in this study underwent intralesional extended curettage, adjuvant cryotherapy using liquid nitrogen, and autogenous iliac crest bone grafting. Follow up for healing of chondroblastoma lesions and detection of any local recurrence was assessed on clinical and radiological bases. The functional outcome was assessed by the Musculoskeletal Tumour Society scoring system. Results The mean follow-up period was 49 months. The average time for bone healing was 7.4 months. Our rate of local recurrence is 7.1 %. Two patients (14.3 %) developed physeal growth arrest. One patient had superficial skin sloughing (7.1 %). None of the cases had pathological fracture. The mean Musculoskeletal Tumour Society functional score was 92.7 %. Conclusion Chondroblastoma is an aggressive benign bone tumour with a high rate of recurrence. The use of high-speed burr combined with adjuvant intralesional cryotherapy and iliac crest autogenous bone grafting is a reliable method of treatment with a low rate of recurrence.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Mashhour

Rahman

2013

International Orthopaedics (SICOT)

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“…The incidence of soft tissue sarcomas and new bone and cartilage malignancies is approximately 1.8 in 100,000 for each [2,11,41], 15% of which occur in the shoulder [12,22]. Salvage of limb and shoulder function after proximal humeral resection for tumors still presents a challenge.…”

Section: Introductionmentioning

confidence: 99%

Does Reverse Shoulder Arthroplasty for Tumors of the Proximal Humerus Reduce Impairment?

Wilde

Boileau

Bracht

2011

Clinical Orthopaedics &Amp; Related Research

104

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Background Normal function of the upper limb is seldom restored after limb-sparing surgery for tumors of the proximal humerus. The literature suggests superior shoulder function is achieved in the short term with reverse total shoulder arthroplasty compared to other techniques when performed for conditions with rotator cuff deficiency. It is unclear whether this superiority is maintained when reverse total shoulder arthroplasty is performed for tumors. Questions/purposes When performed for tumors, we determined whether reverse total shoulder arthroplasty restores function and improves motion, the complications associated with the surgery, and whether reverse total shoulder arthroplasty with autologous grafting is associated with bone resorption. Patients and MethodsWe retrospectively reviewed 14 patients who had undergone reverse total shoulder arthroplasty for tumors of the proximal humerus. Four patients died, leaving nine patients for review. The surviving patients were evaluated clinically and radiographically. The minimum followup was 0.6 years (mean, 7.7 years; range, 0.6-12 years). Results At last followup, mean active abduction was 157°a nd mean functional Constant-Murley score was 76%. One patient had a deep infection and one developed a loose prosthesis; both were treated with single-stage exchange. At last followup, both patients had reasonable function without evidence of infection or loosening. Radiographic graft resorption was seen in all but one patient. Conclusions Our observations suggest, at medium-term followup, reverse total shoulder arthroplasty is a reasonable option for tumors of the proximal humerus. It has low morbidity, restores a mean active abduction of 157°, and limits the impairment of activities of daily living.

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“…It accounts for <1% of all bone tumors. [1][2][3] Recent WHO classification categorizes it as an "intermediate (rarely metastasizing)"…”

Section: Introductionmentioning

confidence: 99%

Intraoperative crush smear cytology of vertebral chondroblastoma: A diagnostic challenge

Tathe

Parate

Jaiswal

et al. 2017

Diagnostic Cytopathology

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Now-a-days intraoperative consultation plays an important role in proper management of patients. Intraoperative crush cytology is widely used in the rapid diagnosis of various tumors, but a very few reports describe the utility of intraoperative cytology for bone lesions. 7 Here, we report a case of vertebral chondroblastoma diagnosed on intraoperative crush smear cytology and later confirmed on histopathology. This case highlights the role of crush cytology in the rapid intraoperative diagnosis of bone tumors.In this brief report, we describe the cytological features of chondroblastoma and discuss its differential diagnosis. | C ASE H I STOR YA 17-year-old male presented with one-year history of back pain.He also complained of progressive weakness and numbness of both lower limbs for 1 month prior to the consultation. His routine investigations were within normal limits. Magnetic resonance imaging (MRI) spine revealed a well defined extradural mass measuring approx 6 cm 3 5 cm 3 3 cm involving predominantly right posterior segment of D 6-7 vertebrae with expansile soft tissue component (Figure 1). The mass showed an extradural intraspinal extension causing cord compression and edema. With a tentative radiological diagnosis of lymphoma, D 6-7 laminectomy was done and near total excision of the tumor was carried out. Postoperatively, the patient recovered well and was able to walk without difficulty. | Intraoperative crush cytologyThe tissue was relatively firm to make the smears. The smears showed dense tissue fragments with well spread cellular smears surrounding

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Benign chondroblastoma.A study of 125 cases

Cited by 306 publications

References 18 publications

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Does Reverse Shoulder Arthroplasty for Tumors of the Proximal Humerus Reduce Impairment?

Intraoperative crush smear cytology of vertebral chondroblastoma: A diagnostic challenge

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