Benign but fatal. A case of a newborn with congenital osteochondroma

Niedźwiecka, Marta; Kaczmarek, Piotr; Krawczyk, Tomasz; Oszukowski, Przemysław; Maroszyńska, Iwona

doi:10.1016/j.bone.2013.02.001

Cited by 2 publications

(3 citation statements)

References 7 publications

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“…Since osteochondromas are typically benign and reach maturity in childhood, progressive pain in an adult with HME is worrisome. 3,5,7,23 Examination findings of a large, tender, nonmobile thoracic mass necessitate further evaluation to rule out an enlarging cartilaginous cap and malignant transformation. 13,24,25 Single osteochondroma has been described as a benign neoplasm, whereas hereditary multiple osteochondromas have been described as hereditary neoplastic syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Many osteochondromas are asymptomatic; however, complications can involve bone, nerve, and soft tissues via mass effect or intrinsic change [1][2][3][4][5][6][7][8][9][10] (Fig 1).…”

Section: Introductionmentioning

confidence: 99%

“…7,[11][12][13] Osteochondromas are common in the appendicular skeleton. Sixty-five percent of these tumors are located around the knee and proximal humerus and 20% arise in the axial skeleton, and of these, approximately 5% occur in the vertebral column.…”

Section: Introductionmentioning

confidence: 99%

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Osteochondroma and Spinal Cord Compression in a Patient With Hereditary Multiple Exostoses: A Case Report

Zoboski

2017

Journal of Chiropractic Medicine

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Objective: The purpose of this report was to describe the presentation of a patient with hereditary multiple exostoses and thoracic spinal cord compression from an osteochondroma. Clinical Features: A 31-year-old female presented to a chiropractic clinic with a history of hereditary multiple exostoses and back pain that had existed since the age of 16 years. She had a past medical history that was remarkable for 3 prior surgeries for mass removal. Examination revealed a left upper midscapular mass with decreased sensation. Intervention/Outcome: Magnetic resonance imaging, computed tomography, and biopsy led to a diagnosis of osteochondroma. These diagnostic modalities confirmed that there was no malignant degeneration. Initial magnetic resonance imaging revealed a large expansive lesion involving the left posterior elements at the region of T3-T4. Subsequent thoracic hemilaminectomy and resection of the spinal tumor with posterior instrumentation and stabilization from T2-T5 resulted in 90% overall subjective improvement. Conclusions: A detailed case history, thorough examination, guided advanced imaging, and biopsy provide important information for the diagnosis and appropriate treatment of expansive lesions in patients with hereditary multiple exostoses. (J Chiropr Med 2017;16:72-77)

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Section: Discussionmentioning

confidence: 99%

“…Many osteochondromas are asymptomatic; however, complications can involve bone, nerve, and soft tissues via mass effect or intrinsic change [1][2][3][4][5][6][7][8][9][10] (Fig 1).…”

Section: Introductionmentioning

confidence: 99%