Benedicte Brøgger: Sosialt entreprenørskapi Norge

Arnesen, Daniel

doi:10.18261/issn.1505-291x-2018-03-06

Cited by 3 publications

(4 citation statements)

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“…In Norway, foreign-born individuals account for almost 90% of TB notifications, and the majority are diagnosed in the first 5 years after arrival 5. Based on molecular surveillance of Mycobacterium tuberculosis strains, the majority of TB in the foreign-born population is assumed to reflect reactivation of LTBI acquired prior to arrival 5. Against this backdrop, Norway has a well-established immigrant screening programme for TB and LTBI.…”

Section: Introductionmentioning

confidence: 99%

Immigrant screening for latent tuberculosis infection: numbers needed to test and treat, a Norwegian population-based cohort study

et al. 2019

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ObjectivesTo estimate the number needed to screen (NNS) and the number needed to treat (NNT) to prevent one tuberculosis (TB) case in the Norwegian immigrant latent tuberculosis infection (LTBI) screening programme and to explore the effect of delay of LTBI treatment initiation.DesignPopulation-based, prospective cohort study.ParticipantsImmigrants to Norway.OutcomeIncident TB.MethodsWe obtained aggregated data on immigration to Norway in 2008–2011 and used data from the Norwegian Surveillance System for Infectious Diseases to assess the number of TB cases arising in this cohort within 5 years after arrival. We calculated the average NNS and NNT for immigrants from the top 10 source countries for TB in Norway and by estimated TB incidence rates in source countries. We explored the sensitivity of these estimates with regard to test performance, treatment efficacy and treatment adherence using an extreme value approach, and assessed the effects of emigration, time to TB diagnosis (to define incident TB) and intervention timing.ResultsNNS and NNT were overall high, with substantial variation. NNT showed numerically stronger negative correlation with TB notification rate in Norway (−0.75 [95% CI −1.00 to −0.44]) than with the WHO incidence rate (IR) (−0.32 [95% CI −0.93 to 0.29]). NNT was affected substantially by emigration and the definition of incident TB. Estimates were lowest for Somali (NNS 99 [70–150], NNT 27 [19–41]) and highest for Thai immigrants (NNS 585 [413–887], NNT 111 [79–116]). Implementing LTBI treatment in immigrants sooner after arrival may improve the effectiveness of the programme.ConclusionUsing TB notifications in Norway, rather than IR in source countries, would improve targeting of immigrants for LTBI management. However, the overall high NNT is a concern and challenges the scale-up of preventive LTBI treatment for significant public health impact. Better data are urgently needed to monitor and evaluate NNS and NNT in countries implementing LTBI screening.

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Section: Introductionmentioning

confidence: 99%

Immigrant screening for latent tuberculosis infection: numbers needed to test and treat, a Norwegian population-based cohort study

et al. 2019

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“…The overall TB incidence rate (IR) in Norway is 6 per 100 000 population per year 4. Foreign-born individuals account for almost 90% of TB notifications and carry an almost 70-fold higher risk of TB IR (42/100 000) compared with the Norwegian-born population, in which the TB IR (0.6/100 000) has reached the pre-elimination phase 4. Although sporadic outbreaks occur, routine molecular surveillance for Mycobacterium tuberculosis strains confirms the overall low TB transmission rate 4.…”

Section: Introductionmentioning

confidence: 99%

“…Foreign-born individuals account for almost 90% of TB notifications and carry an almost 70-fold higher risk of TB IR (42/100 000) compared with the Norwegian-born population, in which the TB IR (0.6/100 000) has reached the pre-elimination phase 4. Although sporadic outbreaks occur, routine molecular surveillance for Mycobacterium tuberculosis strains confirms the overall low TB transmission rate 4. Against this backdrop, screening and preventive treatment of LTBI has gained high priority in Norwegian TB control activities.…”

Section: Introductionmentioning

confidence: 99%

Stratification by interferon-γ release assay level predicts risk of incident TB

Winje

White

Syre

et al. 2018

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“…Tuberkulosediagnosen kan vaere utfordrende, saerlig i land som Norge der forekomsten er blant de laveste i verden. I 2018 fikk 209 personer diagnosen i Norge, hvorav kun 14 % var norskfødte (6). Sykdommen kan mangle på listen over aktuelle differensialdiagnoser som følge av uspesifikk og varierende symptomatologi, som igjen kan føre til forsinket diagnose og økt risiko for smittespredning.…”

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