Benchmarking for surgical site infections among gastrointestinal surgeries and related risk factors: multicenter study in Kuwait

Hamza, Wafaa S; Salama, Mona F.; Morsi, Samar S.; Abdo, Naglaa M.; Al-Fadhli, Mariam

doi:10.2147/idr.s167213

Cited by 16 publications

(18 citation statements)

References 32 publications

(46 reference statements)

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“…The duration of surgery is a risk factor for SSI [24,25]. This study found that EAS patients who had longer surgery were more likely to have an SSI.…”

Section: Discussionmentioning

confidence: 62%

Surgical Site Infection After Emergency Abdominal Surgery in China: A Multicenter Prospective Study

Li¹,

Li²,

Lv³

et al. 2020

Preprint

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Background There is still a lack of relevant studies on surgical site infection (SSI) after emergency abdominal surgery (EAS) in China. This study aims to understand the status of SSI after EAS in China and discuss its risk factors. Materials and Methods All adult patients who underwent EAS in 47 hospitals in China from May 1 to 31, 2018, and from May 1 to June 7, 2019, were enrolled in this study. The basic information, perioperative data, and microbial culture results of infected incision were prospectively collected.The primary outcome measure was the incidence of SSI after EAS, and the secondary outcome variables were postoperative length of stay, ICU admission rate, ICU length of stay, 30-day postoperative mortality, and treatment costs. Univariate and multivariate logistic regression were used to analyze the risk factors.Results A total of 953 patients (age 48.8 ± 17.9 years, male 51.9%) with EAS were included in this study: 71 patients (7.5%) developed SSI after surgery.The main pathogen of SSI was Escherichia coli (culture positive rate 29.6%). Patients with SSI had significantly longer overall hospital (p < 0.001) and ICU stays (p < 0.001), significantly higher ICU admissions (p < 0.001), and medical costs (p < 0.001) than patients without SSI.Multivariate logistic regression analysis showed that male (P = 0.010), high blood glucose level (P < 0.001), colorectal surgery (P < 0.001), intestinal obstruction (P = 0.045) and surgical duration (P = 0.007) were risk factors for SSI, whereas laparoscopic surgery (P < 0.001 = 0.022) was a protective factor. Conclusion This study found a high incidence of SSI after EAS in China. The occurrence of SSI prolongs the patient's hospital stay and increases the medical burden. The study also revealed predictors of SSI after EAS and provides a basis for the development of norms for the prevention of surgical site infection after emergency abdominal surgery.

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“…The duration of surgery is a risk factor for SSI [24,25]. This study found that EAS patients who had longer surgery were more likely to have an SSI.…”

Section: Discussionmentioning

confidence: 62%

Surgical Site Infection After Emergency Abdominal Surgery in China: A Multicenter Prospective Study

Li¹,

Li²,

Lv³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The duration of surgery is a risk factor for SSI 22 , 23 . This study found that EAS patients who had longer surgery were more likely to have an SSI.…”

Section: Discussionmentioning

confidence: 99%

Prospective multicenter study on the incidence of surgical site infection after emergency abdominal surgery in China

et al. 2021

Sci Rep

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There is still a lack of relevant studies on surgical site infection (SSI) after emergency abdominal surgery (EAS) in China. This study aims to understand the incidence of SSI after EAS in China and discuss its risk factors. All adult patients who underwent EAS in 47 hospitals in China from May 1 to 31, 2018, and from May 1 to June 7, 2019, were enrolled in this study. The basic information, perioperative data, and microbial culture results of infected incision were prospectively collected. The primary outcome measure was the incidence of SSI after EAS, and the secondary outcome variables were postoperative length of stay, ICU admission rate, ICU length of stay, 30-day postoperative mortality, and hospitalization cost. Univariate and multivariate logistic regression were used to analyze the risk factors. The results were expressed as the odds ratio and 95% confidence interval. A total of 953 patients [age 48.8 (SD: 17.9), male 51.9%] with EAS were included in this study: 71 patients (7.5%) developed SSI after surgery. The main pathogen of SSI was Escherichia coli (culture positive rate 29.6%). Patients with SSI had significantly longer overall hospital (p < 0.001) and ICU stays (p < 0.001), significantly higher ICU admissions (p < 0.001), and medical costs (p < 0.001) than patients without SSI. Multivariate logistic regression analysis showed that male (P = 0.010), high blood glucose level (P < 0.001), colorectal surgery (P < 0.001), intestinal obstruction (P = 0.045) and surgical duration (P = 0.007) were risk factors for SSI, whereas laparoscopic surgery (P < 0.001) was a protective factor. This study found a high incidence of SSI after EAS in China. The occurrence of SSI prolongs the patient's hospital stay and increases the medical burden. The study also revealed predictors of SSI after EAS and provides a basis for the development of norms for the prevention of surgical site infection after emergency abdominal surgery.

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“…Another weakness of this meta-analysis was the inclusion of different types of surgery (e.g., breast, vascular, orthopaedic, or colorectal surgery) which considerably differ in their SSI rates. Even emergency surgery was compared to elective surgery and open vs laparoscopic surgery, although one of the well documented benefits of laparoscopic surgery is the low rate of SSI [19] and an inverse relationship of SSI [20].…”

Section: Discussionmentioning

confidence: 99%

Do antibacterial skin sutures reduce surgical site infections after elective open abdominal surgery? - Study protocol of a prospective, randomized controlled single center trial

Matz

Teuteberg

Wiencierz

et al. 2019

Trials

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Background Surgical site infections (SSI) remain one of the most common complications in conventional abdominal surgery with an incidence between 4% and 19% (Sandini et al., Medicine (Baltimore) 95:e4057, 2016) in the literature. It is unclear whether the use of coated suture material for skin closure reduces the risk of SSI. In line with in-vitro results, we hypothesize that the use of antibacterial skin sutures (triclosan-coated poliglecaprone 25) reduces the rate of SSI after open abdominal surgery. Methods/design To prevent SSI, triclosan-coated poliglecaprone 25 sutures will be tested against un-coated suture material for skin closure after elective open abdominal surgery of 364 patients. The study is planned as a single-center, prospective randomized controlled trial. Patients will be followed for 30 days after surgery to detect and document wound complications. The rate of SSI after 30 days will be analyzed in both groups. Discussion If we can confirm the proposed hypothesis in our study, this could be a promising and feasible approach to lower SSI after open abdominal surgery. By lowering the rate of SSI this might offer a cost-saving and morbidity-reducing procedure. Trial registration German Clinical Trials Register, DRKS00010047 . Registered on 05.01.2017. Electronic supplementary material The online version of this article (10.1186/s13063-019-3492-3) contains supplementary material, which is available to authorized users.

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Benchmarking for surgical site infections among gastrointestinal surgeries and related risk factors: multicenter study in Kuwait

Cited by 16 publications

References 32 publications

Surgical Site Infection After Emergency Abdominal Surgery in China: A Multicenter Prospective Study

Surgical Site Infection After Emergency Abdominal Surgery in China: A Multicenter Prospective Study

Prospective multicenter study on the incidence of surgical site infection after emergency abdominal surgery in China

Do antibacterial skin sutures reduce surgical site infections after elective open abdominal surgery? - Study protocol of a prospective, randomized controlled single center trial

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