Beiträge zur Biologie und Physiologie von Arum maculatum.

Schmucker, Th.

doi:10.1016/s0367-1615(17)32906-3

Cited by 10 publications

(7 citation statements)

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“…The tbermogenic activity of the male flowers correlates with the release of an odour that is fruitlike and pleasant ( Fig. 2b; see also Schmucker, 1925). It can be detected until the male flowers stop heat production and the pollen grains are released ( Fig.…”

Section: Discussionmentioning

confidence: 90%

Dynamics of thermogenesis and structure of epidermal tissues in inflorescences of Arum maculatum

Bermadinger-Stabentheiner

Stabentheiner

1995

New Phytologist

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The temporal dynamics and spatiaJ distribution of heat production by inflorescences of Arum maculatum L. were investigated by infra-red thermography. Two centres of he^t production, tbe appendix and the male flowers, and three tbermogenic phases, two of tbe male flowers and one of tbe appendix, could be obser\ed. On tbe first day of flowering, when the spatbc was still firmly closed, the male flowers became tberniogenic ( = first thfrmogenic phase of tbe inflorescence) and reacbed surface temperatures of 4-l-8

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Section: Discussionmentioning

confidence: 90%

Dynamics of thermogenesis and structure of epidermal tissues in inflorescences of Arum maculatum

Bermadinger-Stabentheiner

Stabentheiner

1995

New Phytologist

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“…Investigations into the cyanide‐resistant respiration of plants lead to the discovery of the second terminal oxidase in the mitochondrial respiratory chain called the AOX. AOX was first identified in plants in the 1920s and it has since been thoroughly researched. Indeed, most of the information we have about the AOX class of proteins today is as a result of the intensive research carried out on AOXs from plants.…”

Section: Aox In Human and Veterinary Parasitesmentioning

confidence: 99%

Alternative oxidase inhibitors: Mitochondrion‐targeting as a strategy for new drugs against pathogenic parasites and fungi

Ebiloma

Balogun

Cueto-Díaz

et al. 2019

Medicinal Research Reviews

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The alternative oxidase (AOX) is a ubiquitous terminal oxidase of plants and many fungi, catalyzing the four‐electron reduction of oxygen to water alongside the cytochrome‐based electron transfer chain. Unlike the classical electron transfer chain, however, the activity of AOX does not generate adenosine triphosphate but has functions such as thermogenesis and stress response. As it lacks a mammalian counterpart, it has been investigated intensely in pathogenic fungi. However, it is in African trypanosomes, which lack cytochrome‐based respiration in their infective stages, that trypanosome alternative oxidase (TAO) plays the central and essential role in their energy metabolism. TAO was validated as a drug target decades ago and among the first inhibitors to be identified was salicylhydroxamic acid (SHAM), which produced the expected trypanocidal effects, especially when potentiated by coadministration with glycerol to inhibit anaerobic energy metabolism as well. However, the efficacy of this combination was too low to be of practical clinical use. The antibiotic ascofuranone (AF) proved a much stronger TAO inhibitor and was able to cure Trypanosoma vivax infections in mice without glycerol and at much lower doses, providing an important proof of concept milestone. Systematic efforts to improve the SHAM and AF scaffolds, aided with the elucidation of the TAO crystal structure, provided detailed structure‐activity relationship information and reinvigorated the drug discovery effort. Recently, the coupling of mitochondrion‐targeting lipophilic cations to TAO inhibitors has dramatically improved drug targeting and trypanocidal activity while retaining target protein potency. These developments appear to have finally signposted the way to preclinical development of TAO inhibitors.

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“…3.1. Influence of the light/dark regime The first experiments indicating an effect of light & darkness on the anthesis of arum lilies were performed by SCHMUCKER (1925) with Arum maculatum. With very few exceptions, inflorescences transferred to darkness a few days before expected opening-time, and then kept in darkness, never unfolded.…”

Section: Experimental Partmentioning

confidence: 99%

“…KNOLL 1926M. KNOLL , 1956KULLENBERG 1953;LAMARCK 1778;MEEUSE 1959MEEUSE a and b, 1961MEEUSE , 1968MEEUSE & HATCH 1960; VAN DER PUL 1933, 1937PRIME 1960;VOGEL 1963), plant physiologists (MATILE 1958;SCHMUCKER 1925SCHMUCKER , 1930 and plant biochemists (VAN HERK 1937 a, band c;JAMES & BEEVERS 1950;HESS 1961HESS , 1964HESS & MEEUSE 1967;OLASON 1967;SIMON 1962;SIMON & CHAPMAN 1961;SMITH & MEEUSE 1966).…”

Section: Introductionmentioning

confidence: 99%

Time, Space, Light and Darkness in the Metabolic Flare-Up of the Sauromatum Appendix*

Meeuse

Buggeln

1969

Acta Botanica Neerlandica

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In order to arrive at a better understanding of the flowering events in certain arum lilies, an effort has been made to integrate the relevant information provided by plant physiologists, naturalists, and plant biochemists with our own recent experiments. In Sauromatum guttatum Schott, the metabolic flare-up which, on the first day of flowering, occurs in the so called appendix of the inflorescence, is triggered by an agent (Van Herk's calorigen) that arises in the male flower primordia when these are exposed to the proper regime of light and darkness. A single, 5 to 6 hour exposure to darkness of an inflorescence kept in constant light suffices to induce the flare-up, a peak in heat-and CO.-production occurring about 40 to 45 hours after the beginning of the "dark shot". Repeated exposures to darkness, at 24-hour intervals, shorten both the 40 to 45-hour lag-time and the critical length of each dark period, so that good responses occur after about 36 hrs. with a series of dark shots of 2 to 3 hours duration. The available evidence indicates that the site for perception of the second effective dark shot is in the appendix. After a single 6-hour dark shot, amputated appendices still develop heat and smell, provided the amputation is carried out at least 8 to 9 hours after the end of the dark shot. This indicates that the active principle formed in the male flower primordia as the result of the dark shot is not immediately released into the appendix. However, distribution in the appendix must be fast, since the various parts of the latter (base, middle and tip) heat up almost simultaneously, even though they do not display demonstrable differences in true lag-time, i.e., in the period between the release of the triggering compound and the peak in metabolic activity; injection of extracted calorigen into properly treated appendix-sections always leads to a peak in metabolic activity about 30 hours later. In intact inflorescences, amputation or wounding of the spathe leads to a metabolic flare-up 36 hours later. The implications of the uncovered facts are briefly discussed.

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Beiträge zur Biologie und Physiologie von Arum maculatum.

Cited by 10 publications

References 1 publication

Dynamics of thermogenesis and structure of epidermal tissues in inflorescences of Arum maculatum

Dynamics of thermogenesis and structure of epidermal tissues in inflorescences of Arum maculatum

Alternative oxidase inhibitors: Mitochondrion‐targeting as a strategy for new drugs against pathogenic parasites and fungi

Time, Space, Light and Darkness in the Metabolic Flare-Up of the Sauromatum Appendix*

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