Beiträge zu den Augenhintergrundsveränderungen bei Sclerosis multiplex

Orban, T

doi:10.1159/000302702

Cited by 11 publications

(2 citation statements)

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“…If parallel pathological processes develop in the retina and in the brain in clinical MS it Seems reasonable to suppose that PR occurs more frequently during the active stages of MS. A Possible correlation between PR and neurological disease activity has been suggested by Haarr (2) and since then by other authors (17,18), but none of them defined the state of neurological disease activity. Bamford (19) supported the hypothesis with a study of 14 patients with PR of whom eight were in a P~OgreSSiVe group.…”

Section: Discussionmentioning

confidence: 94%

Neurological disease activity in multiple sclerosis patients with periphlebitis retinae

Engell

2009

Acta Neurologica Scandinavica

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ABSTRAm -Periphlebitis retinae (PR) in multiple sclerosis (MS) is seen as cuffs around veins in the otherwise normal retinae. The frequency of PR in MS varies considerably between different series, approximately from 5 to 25%.The aim of the present study was to investigate if PR, when present, is correlated to neurological disease activity. No similar study has been performed to the author's knowledge.The prevalence of PR in a hospital material of 135 MS patients was 15%, compared to the frequency of 5 % found in 168 MS patients examined at a Rehabilitation Center. Thus a three times higher frequency was found in the hospital material which comprised more patients with active disease.The status of neurological disease activity was assessed in 27 patients at the occurrence of PR. One patient only had stationary disease. The frequency of malignant MS in the 27 PR patients was 26% versus 9%. The present study suggests a correlation between neurological disease activity and PR in MS patients.

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Section: Discussionmentioning

confidence: 94%

Neurological disease activity in multiple sclerosis patients with periphlebitis retinae

Engell

2009

Acta Neurologica Scandinavica

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“…Bamford et al [4] reported a significant associa tion between perivenous sheathing and severe progres sion of neurological disability. A relationship with MS activity has been suggested by Orban [19] and then by others based on clinical series [20,21] or pathological studies [9]. The small number of patients, or the lack of a clear definition of neurological status and disease phase limit the possibility of drawing final conclusions on this subject.…”

Section: Discussionmentioning

confidence: 99%

Retinal Periphlebitis in Multiple Sclerosis: A Marker of Disease Activity?

Tola

Granieri²,

Casetta³

et al. 1993

Eur Neurol

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This study was performed in order to verify the prevalence of retinal periphlebitis and other ocular changes in a well-defined population of multiple sclerosis (MS) patients, and to correlate the presence of these features with some clinical variables which characterize the disease. 110 MS-affected subjects were submitted to a standard ophthalmologic examination including a biomicroscopical evaluation of the fundus oculi. The prevalence of retinal sheathing in MS patients was found to be nearly 36 %. It is significantly higher in patients evaluated in an active phase of the disease than in those examined in a stationary phase.

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Diseases of the Retina and Optic Nerve

Hollenhorst¹

1958

Archives of Ophthalmology

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Beiträge zu den Augenhintergrundsveränderungen bei Sclerosis multiplex

Cited by 11 publications

References 0 publications

Neurological disease activity in multiple sclerosis patients with periphlebitis retinae

Neurological disease activity in multiple sclerosis patients with periphlebitis retinae

Retinal Periphlebitis in Multiple Sclerosis: A Marker of Disease Activity?

Diseases of the Retina and Optic Nerve

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