Beitrag zur visceralen Lepra

Doutrelepont,; Wolters, Max

doi:10.1007/bf01842659

Cited by 22 publications

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“…Since the first evidence of pulmonary leprosy was made by Bonome, the discovery was later proved by many authors, for example, Joseph Doutrelepont (1834–1918), 15 Giuseppe Scagliosi (nd), 16 Elena Fambri (1886‐nd) 17 and Victor Babes (1854–1926) 18 observed the same alterations and confirmed the presence of leprosy in the lungs as described by Bonome.…”

Section: Discussionsupporting

confidence: 57%

“…13 It is also known that nervous tissue is fundamental in the development and modelling of skeletal tissue, so it is possible that the remodelling also happens because of impaired neural signalling. 14 Since the first evidence of pulmonary leprosy was made by Bonome, the discovery was later proved by many authors, for example, Joseph Doutrelepont (1834-1918), 15 Giuseppe Scagliosi (nd), 16 Elena Fambri (1886-nd) 17 and Victor Babes (1854-1926) 18 observed the same alterations and confirmed the presence of leprosy in the lungs as described by Bonome.…”

Section: Discussionmentioning

confidence: 60%

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Augusto Bonome and his revolutionary studies on leprosy in the early 20th century

Valle,

Magno,

Zanatta

2023

Acad Dermatol Venereol

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BackgroundAugusto Bonome (1857–1922), professor at the University of Padua until 1922, was involved in a study about a particular kind of pulmonary leprosy, being the first to testify the lepromatous alterations also in the deepest parts of the respiratory tract, even though the same Gerhard Hansen (1841–1912) had denied the possibility that lungs could host Mycobacterium leprae.ObjectivesIt is necessary to reevaluate the research done by Bonome to also demonstrate how it can still be relevant today in further comprehension of leprosy.MethodsBonome's advances in leprosy studies are testified by some specimens from the Morgagni Museum of Pathological Anatomy of the University of Padua. Among the specimens, there is a peculiar case of advanced tuberous leprosy in an adolescent, who died in 1908, of which the face, the larynx, the hands and genitals are still preserved today in the Museum.ResultsThrough autoptic and histological analysis of this specimen, Bonome succeeded in identifying a peculiar case of bone toxoid‐infectious dystrophy besides characteristic leprous laryngitis, which caused the death of the young leprosy patient.ConclusionsThe results confirmed the innovative research carried on by Bonome during his medical career, being among the first to offer an important contribution to improving and revolutionary knowledge on leprosy which could still be useful today.

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Section: Discussionsupporting

confidence: 57%