Behavioral Reactions and Cognitive Functions in Rats With Vascular Model of Alzheimer's Type Dementia at the Different Stages of Disease Before and After Stem Cell Correction
Abstract:Background. The last researches offer to conduct the study of Alzheimer disease (AD) mechanisms using diverse experimental models. However, it was not investigated the behavioral and cognitive impairment in rats at the different stages of vascular model of dementia of Alzheimer’s type developed by us.
Subjects and methods. The experiment was performed on 32 male WAG rats weighing 180-250 g which were divided into 4 groups. Rats from group 1 and 3 were injected by aqueous solution of sodium nitrite at a d… Show more
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