Behavioral Inhibition in Boys with Sex Chromosome Aneuploidies Compared to a Clinical Sample

Fjermestad, Krister W.; Wahlborg, Marte Strandheim; Stokke, Simen; Haugland, Bente Storm Mowatt; Havik, Odd E.; Wergeland, Gro Janne

doi:10.1007/s41252-017-0016-6

Cited by 2 publications

(2 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Individuals tend to have greater issues in the domains of inattention and hyperactivity/impulsivity, which may contribute to lower adaptive functioning overall (Bardsley et al 2013 ; Joseph et al 2018 ; Kuiper et al 2021 ; Ross et al 2015 ; Tartaglia et al 2012 ). Similarly, children with XYY show deficits in both internalizing and externalizing behaviors, with externalizing behaviors such as impulsivity, behavioral regulation, thought and attention problems, and aggression tending to be worse (Fjermestad et al 2017 ; Operto et al 2019 ; Ross et al 2012 ). Although externalizing behaviors are more prominent, some individuals with XYY also show internalizing behavior problems, such as withdrawal (Fjermestad et al 2017 ; Lalatta et al 2012 ; Operto et al 2019 ).…”

Section: Neurodevelopmental Featuresmentioning

confidence: 99%

“…Similarly, children with XYY show deficits in both internalizing and externalizing behaviors, with externalizing behaviors such as impulsivity, behavioral regulation, thought and attention problems, and aggression tending to be worse (Fjermestad et al 2017 ; Operto et al 2019 ; Ross et al 2012 ). Although externalizing behaviors are more prominent, some individuals with XYY also show internalizing behavior problems, such as withdrawal (Fjermestad et al 2017 ; Lalatta et al 2012 ; Operto et al 2019 ). Comorbid mood disorders, such as anxiety and depression, tend to be more common in instances where there is a diagnosis of another neurodevelopmental disorder (Bardsley et al 2013 ; Tartaglia et al 2012 ).…”

Section: Neurodevelopmental Featuresmentioning

confidence: 99%

See 1 more Smart Citation

Understanding the phenotypic spectrum and family experiences of XYY syndrome: Important considerations for genetic counseling

et al. 2023

View full text Add to dashboard Cite

XYY syndrome is characterized by a variable neurodevelopmental phenotype, with features including developmental delays, cognitive impairments, and an increased risk for mental health conditions. There are two recent developments that have primarily motivated this review. The first is the increased use of non-invasive prenatal screening (NIPS), which will likely result in more individuals being diagnosed with XYY prenatally. As such, health care providers (HCPs) both within genetics and outside of the specialty are more likely to encounter this diagnosis in the future. The second is advances in the understanding of the phenotypic variability of XYY through biobank and deep phenotyping efforts. As the phenotypic spectrum of XYY syndrome continues to expand, families will face greater uncertainty when receiving this diagnosis. Given both of these developments, HCPs will need to have up-to-date and accurate information about XYY to better counsel families. Furthermore, the ability to employ effective counseling techniques, such as anticipatory guidance, will aid in supporting and guiding families through the diagnostic journey. This review aims to provide insight on the neurodevelopmental and psychosocial aspects of XYY syndrome by discussing current research and borrowing from the relevant psychosocial literature of other genetic conditions. In this way, we hope to equip HCPs with the ultimate goal of improving the care and support provided to individuals with XYY and their families.

show abstract