Behavioral evaluating methods in the objective clinical assessment of motor function after experimental brachial plexus reconstruction in the rat

Bertelli, Jayme Augusto; Mira, Jean‐Claude

doi:10.1016/0165-0270(93)90068-3

Cited by 136 publications

(109 citation statements)

References 6 publications

Supporting

Mentioning

108

Contrasting

Order By: Relevance

“…Formation of the brachial plexus and distribution of its peripheral branches in rat and human were reported to be more similar compared to many other experimental animals. 1,3,5,9 The similarity in organization of the brachial plexuses in rat and human makes it possible to prefer the rats especially in experimental surgery and microsurgery studies. Therefore, this kind of morphologic and morphometric studies on rats are intensely required.…”

Section: Discussionmentioning

confidence: 99%

“…3,5,9,10 It is reported that the brachial plexus and its terminal branches provide a good experimental model which can be used to assess the development and normal control of muscle function, examine the mechanisms underlying functional recovery, and test the effects of treatments to enhance recovery. 3,10 The anatomic location and structure of brachial plexus should be grasped by the surgeons dealing with its surgery due to its complex structure, relation to the neighboring structures and anatomic features of the region it is located as well as taking into consideration that the brachial plexus may exhibit frequent variations. 5,7,11,12 At the beginning of the development, while myotom elongations taking place, they take the nerve fibers together with them originating from the same segment.…”

Section: öZba¤ D Et Almentioning

confidence: 99%

See 1 more Smart Citation

Morphologic and morphometric investigation of plexus brachialis in rat

Özbağ¹

2009

Anatomy

View full text Add to dashboard Cite

Objectives: Our aim was to investigate the morphologic and morphometric features of brachial plexus in rat and to evaluate the findings with that of the human in classical textbooks comparatively. Methods:This study was carried out on 100 brachial plexuses of 50 adult wistar albino rats (240-280 gr) (25 males and 25 females). The overlying tissues were incised for the evaluation of brachial plexus in the axillary region. After then brachial plexus was prepared with the microdissection technique and evaluated in terms of its formation. We made the measurements related to the brachial plexus and extremities; length of upper (anterior) extremities, length and width of axillary region, brachial plexus, and roots of spinal nerves. We also noted the formation shape of brachial plexus. Results:We found that the brachial plexus of rat was formed by C5, C6, C7, C8 and Th1 spinal nerves. Sometimes, fibers from C4 might connect with C5. The formation of brachial plexus at root level varied from each other in rats. On the other hand, some roots were thick while some of them were thin in shape. Of the contributing spinal nerves to the brachial plexus (C5-8, Th1), mean width was between 0.7-1.1 mm, mean length of merging to the trunk was 2.2-4.06 mm, while mean width of brachial plexus was 7.8 mm, mean length was detected as 9.5 mm. There was significant correlation with respect to p<0.05 and p<0.01 between the length and width values of the upper extremity and the values of the brachial plexus itself as well as the spinal nerves forming the plexus. In the histologic examination, mean axonal count was between 4000-4500 in each mm 2 at the level of spinal nerve roots. The diameter and the number of axons were inversely proportional to each other. Conclusion:Comparative knowledge on the morphometric and morphologic features of brachial plexus in rat and human can help the investigators to achieve successful results in experimental surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: öZba¤ D Et Almentioning

confidence: 99%

Morphologic and morphometric investigation of plexus brachialis in rat

Özbağ¹

2009

Anatomy

View full text Add to dashboard Cite

show abstract

“…To determine functional nerve recovery in the rat forelimbs, we performed a grooming test, 6 which consisted of spraying water over the animal's face to elicit grooming movements of the forepaws toward the head. In normal grooming, the animal raised both forelimbs, licked them, and reached up behind the ears.…”

Section: Grooming Testmentioning

confidence: 99%

Functional Motor Nerve Regeneration Without Motor-Sensory Specificity Following End-to-Side Neurorrhaphy: An Experimental Study

Lin

Ding

et al. 2011

The Journal of Hand Surgery

View full text Add to dashboard Cite

“…Both contractures and autotomy can interfere with the results of functional experiments. Since the dis-tance to the target organs (muscles and skin) is short in the rat forelimb, reinnervation is quicker, and the time required for functional recovery is less than in hindlimbs (Bertelli and Mira, 1993;Bontioti et al, 2003). The complexity of the forelimb nerves and their branches offers various experimental opportunities, since selective injuries can be easily applied to motor or sensory branches compared to hind limb nerves (Bontioti et al, 2003).…”

mentioning

confidence: 99%

Microscopic anatomy of brachial plexus branches in Wistar rats

Santos

Suaid

Fazan

et al. 2007

The Anatomical Record

View full text Add to dashboard Cite

In the present study, we analyze the morphology and morphometry of the lateral proper digital nerve of the third finger, and of the proximal and distal segments of the ulnar, median, and radial nerves, in Wistar rats 4 or 7 weeks old. The fascicular area and diameter were generally significantly greater in the proximal compared to distal segments and tended to be larger in 7-week-old compared to 4-week-old rats (e.g., median nerve area of 0.13 mm 2 for the proximal and 0.07 mm 2 for distal segments in 4-weekold rats, and 0.17 and 0.10 mm 2 , respectively, for the proximal and distal segments of 7-week-old rats). The number of fascicles was significantly greater while the number of myelinated fibers was significantly less in the distal segments (e.g., 1,359 and 509 myelinated fibers, respectively, in the proximal and distal segments of the radial nerve 4-week-old rats). There was no significant difference in these parameters between the two age groups. The diameter of the myelinated fibers and their respective axons increased from 4 to 7 weeks of age (e.g., myelinated fiber diameter of 4.10 mm in 4-week-old animals and 4.7 mm in the ulnar nerve proximal segment of 7-week-old rats). The g-ratio regression line (axon diameter vs. fiber diameter quotient) was outlined for all the nerves studied here. Differences in myelinated fiber density were detected between the segments of the radial nerve, accompanying the number of myelinated fibers. Detailed knowledge of the microscopic anatomy of rat forelimb nerves provides control data for comparison with studies of experimentally induced neuropathies, which can shed more light on human neuropathies. Anat Rec, 290:477-485, 2007. 2007 Wiley-Liss, Inc.

show abstract

Behavioral evaluating methods in the objective clinical assessment of motor function after experimental brachial plexus reconstruction in the rat

Cited by 136 publications

References 6 publications

Morphologic and morphometric investigation of plexus brachialis in rat

Morphologic and morphometric investigation of plexus brachialis in rat

Functional Motor Nerve Regeneration Without Motor-Sensory Specificity Following End-to-Side Neurorrhaphy: An Experimental Study

Microscopic anatomy of brachial plexus branches in Wistar rats

Contact Info

Product

Resources

About