Behavioral effects of essential oils from Lippia alba (Mill.) N.E. Brown chemotypes

Vale, Tiago Gurgel do; Matos, F. J. A.; Lima, Thereza Christina Monteiro de; Viana, G. S. B.

doi:10.1016/s0378-8741(98)00215-3

Cited by 72 publications

(67 citation statements)

References 11 publications

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“…Some of these can be found in EOs from Bacharis species, such as α-pinene, limonene, linalool, myrcene, α-terpineol, and the sesquiterpenes eudesmene, α-and β-eudesmol, and caryophyllene oxide (Agostini et al, 2005;Lago et al, 2008;Ascari et al, 2009;Retta et al, 2009;Simonsen et al, 2009). Monoterpenes identified in the EO samples here evaluated that can be related to hypno-sedative properties include α-pinene (Sayyah et al, 2004) and limonene (Vale et al, 1999;2002).…”

Section: Discussionmentioning

confidence: 85%

Sedative effects of essential oils obtained fromBaccharis uncinella

Ascari

Sens²,

Nunes

et al. 2011

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 85%

Sedative effects of essential oils obtained fromBaccharis uncinella

Ascari

Sens²,

Nunes

et al. 2011

Pharmaceutical Biology

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“…Extracts and infusions of leaves and flowers of L. alba are used in the popular medicine of several countries for the treatment of colds, flu, bronchitis, coughs, asthma, fever, diarrhea and other disorders (Alea et al, 1996;Vale et al, 1999). Spasmolytic, analgesic, cytostatic, anticonvulsivant and antiulcerogenic activities have been proved and attributed to the essential oils of L. alba (Alea et al, 1996;Matos, 1998;Viana et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Genetic variation among South Brazilian accessions of Lippia alba Mill. (Verbenaceae) detected by ISSR and RAPD markers

et al. 2009

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Twenty-seven accessions of Lippia alba Mill. collected in Rio Grande do Sul state, Brazil, were analysed by ISSR and RAPD markers to evaluate their genetic variability and relationships. Six ISSR primers and four RAPD primers generated 120 amplified fragments, most of which were polymorphics. The overall genetic variability among accessions was very high when compared with other plant species. The hierarchical analysis of molecular data (UPGMA) showed low relationship between accessions, and no grouping between accessions of the same chemotype. Canonical functions allowed identifying some variables related with the chemical characteristics of the essential oils. Both ISSR and RAPD markers were efficient to address the genetic diversity of L. alba, and may contribute to the conservation and breeding of this increasingly important aromatic and medicinal species.Keywords: molecular relationship, ISSR, RAPD, Lippia alba, Verbenaceae. Variabilidade genética entre acessos sul-brasileiros de Lippia alba Mill. (Verbenaceae) detectada por ISSR e RAPD ResumoVinte e sete acessos de Lippia alba Mill. coletados no Rio Grande do Sul, Brasil, foram analisados por marcadores ISSR e RAPD visando avaliar a variabilidade genética e as relações entre acessos. Seis sequencias iniciadoras de ISSR e quatro de RAPD geraram 120 fragmentos amplificados, a maior parte dos quais apresentaram algum grau de polimorfismo. A variabilidade genética geral entre acessos foi muito elevada quando comparada com outras espécies vegetais. A análise hierárquica dos dados moleculares (UPGMA) mostrou baixa relação entre acessos, e não houve formação de agrupamentos entre acessos pertencentes ao mesmo quimiotipo. Análise de funções canônicas permitiu identificar algumas variáveis relacionadas com as características químicas dos óleos essenciais. Tanto os marcadores ISSR como RAPD foram eficientes para avaliar a diversidade genética em L. alba e devem contribuir para a conservação e melhoramento desta importante espécie aromática e medicinal.

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Análise do óleo essencial de folhas de três quimiotipos de Lippia alba (Mill.) N. E. Br. (Verbenaceae) cultivados em condições semelhantes

Tavares¹,

Julião²,

Lopes³

et al. 2005

Rev. bras. farmacogn.

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INTRODUÇÃOLippia alba ocorre nas américas Central e do Sul, habitando praticamente todas as regiões do Brasil, onde é muito empregada como medicinal, pelas suas propriedades sedativa, carminativa, analgésica, espasmolítica e emenagoga (Zétola et al., 2002;Vale et al., 1999;Matos et al., 1996) Unitermos: Lippia alba, Verbenaceae, óleo essencial, citral, carvona, linalol.ABSTRACT: "Analysis of the essential oil from leaves of three Lippia alba (Mill.) N. E. Br. (Verbenaceae) chemotypes cultivated on the same conditions". The composition of Lippia alba essential oil varies in a manner that different chemotypes are recognized. This work deals with the analysis of the essential oil from three chemotypes of L. alba from different regions of Brazil, cultivated in similar conditions, to verify if the differences in their chemical composition can be due to environmental conditions or may be due to infra-specifi c genetic variation. The infl uence of fl owering was investigated regarding essential oil yield and composition. The chemotypes producing citral, carvone and linalol were denominated chemotypes 1, 2 and 3, respectively. The essential oils were obtained by hydrodistillation of the leaves, at fl owering and vegetative growth stages. Essential oils were analyzed by GC and GC/MS. A better yield was obtained from plants at vegetative stage. The composition of the essential oils remained unchanged after cultivation in the same conditions, and did not vary qualitatively during fl owering and vegetative periods. Relative percentages of the major compounds changed during fl owering period. Data obtained allow us to reinforce the idea that differences in the essential oil composition of the three chemotypes are due to genotypic variations and that the essential oil extraction during the vegetative period enables a better yield and higher percentages of the major compounds.

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Behavioral effects of essential oils from Lippia alba (Mill.) N.E. Brown chemotypes

Cited by 72 publications

References 11 publications

Sedative effects of essential oils obtained fromBaccharis uncinella

Sedative effects of essential oils obtained fromBaccharis uncinella

Genetic variation among South Brazilian accessions of Lippia alba Mill. (Verbenaceae) detected by ISSR and RAPD markers

Análise do óleo essencial de folhas de três quimiotipos de Lippia alba (Mill.) N. E. Br. (Verbenaceae) cultivados em condições semelhantes

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