Behavioral and activities of daily living inventories in the diagnosis of frontotemporal lobar degeneration and Alzheimer's disease

Bahia, Valéria Santoro; Silva, Mari-Nilva Maia da; Viana, Rene; Smid, Jerusa; Damin, Antonio Eduardo; Radanovic, Márcia; Nitrini, Ricardo

doi:10.1590/s1980-57642009dn20200006

Cited by 9 publications

(10 citation statements)

References 37 publications

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“…Several instruments are available for assessing behavioral symptoms in patients with dementia including the Frontal Behavioral Inventory (FBI), which was devised specifically to assess the behavioral disturbance in FTLD. 32 - 34 Kertesz et al, 35 2000, administered the FBI in patients with FTD, PNFA, AD, vascular dementia and depressive disorder. They demonstrated that the scale correctly classified 92.7% of the FTD patients and demonstrated high internal consistency and inter-rater reliability.…”

Section: Discussionmentioning

confidence: 99%

Accuracy of neuropsychological tests and the Neuropsychiatric Inventory in differential diagnosis between Frontotemporal dementia and Alzheimer's disease

Bahia

Viana

2009

Dement. neuropsychol.

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The differential diagnosis between frontotemporal dementia (FTD) and Alzheimer’s disease (AD) is sometimes difficult.ObjectivesTo verify the accuracy of neuropsychological tests and a behavioral disorders scale in the differential diagnosis between FTLD and AD.MethodsRetrospective data on 12 FTD patients and 12 probable AD patients were analyzed. The scores on neuropsychological tests (MMSE score, reverse digit span, delayed recall for drawings, semantic fluency of animals) and the Neuropsychiatric Inventory (NPI) in both groups were compared.ResultsBoth groups had similar performance on neuropsychological tests. All FTD patients and 50% of AD patients had neuropsychiatric abnormalities. The NPI score was 58.0±19.3for the FTD patients, and 3.6±4.7for the AD patients (p< 0.01). Using a NPI cut-off score of 13, the sensitivity and specificity were 100% in this sample. The four most common neuropsychiatric disturbances in FTD patients were: apathy, aberrant motor behavior, disinhibition and eating abnormalities. Apathy and dysphoria/depression were the most common behavioral symptoms among the AD patients.ConclusionsIn this study, NPI was found to be a useful tool for the differential diagnosis between FTD and AD. The neuropsychological tests commonly used in the medical office were unable to distinguish between the two groups.

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Section: Discussionmentioning

confidence: 99%

Accuracy of neuropsychological tests and the Neuropsychiatric Inventory in differential diagnosis between Frontotemporal dementia and Alzheimer's disease

Bahia

Viana

2009

Dement. neuropsychol.

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“…The Disability Assessment for Dementia was also adapted for Brazil 11 and seems to be useful for the characterization of functionality in frontotemporal dementia and AD, assessing both BADLs and IADLs as well as leisure activities, although these two groups do not show differences in functional performance. 12 The BADL index was developed by Sidney Katz in 1963 13 to study the results of treatment and prognosis among older and chronically ill people. The grades of the index summarize overall performance in bathing, dressing, going to the bathroom, transferring, continence, and feeding.…”

Section: Introductionmentioning

confidence: 99%

Development, validity, and reliability of the General Activities of Daily Living Scale: a multidimensional measure of activities of daily living for older people

Paula

Bertola

Ávila

et al. 2014

Rev. Bras. Psiquiatr.

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Objective: To propose and evaluate the psychometric properties of a multidimensional measure of activities of daily living (ADLs) based on the Katz and Lawton indices for Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods: In this study, 85 patients with MCI and 93 with AD, stratified by age (f 74 years, . 74 years), completed the Mini Mental State Examination (MMSE) and the Geriatric Depression Scale, and their caregivers completed scales for ADLs. Construct validity (factor analysis), reliability (internal consistency), and criterion-related validity (receiver operating characteristic analysis and logistic regression) were assessed. Results: Three factors of ADL (self-care, domestic activities, and complex activities) were identified and used for item reorganization and for the creation of a new inventory, called the General Activities of Daily Living Scale (GADL). The components showed good internal consistency (. 0.800) and moderate (younger participants) or high (older participants) accuracy for the distinction between MCI and AD. An additive effect was found between the GADL complex ADLs and global ADLs with the MMSE for the correct classification of younger patients. Conclusion: The GADL showed evidence of validity and reliability for the Brazilian elderly population. It may also play an important role in the differential diagnosis of MCI and AD.

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“…Carvalho et al [ 13 ] found no significant difference in functional communication between AD and FTLD patients. Similarly, Bahia et al [ 14 ] found no significant differences between patients with AD and FTLD on DAD scores. In their sample, DAD did not prove accurate for differential diagnosis of these dementia types.…”

Section: Discussionmentioning

confidence: 94%

Functional Status in Behavioral Variant Frontotemporal Dementia: A Systematic Review

Lima-Silva

Bahia

Nitrini

et al. 2013

BioMed Research International

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The aim was to conduct a systematic review of studies that described the functional profile of patients with behavioral variant frontotemporal dementia (bvFTD), published between 2000 and 2013. The bibliographic search was conducted using the terms “frontotemporal dementia” and “frontotemporal lobar degeneration” in combination with “independence,” “functionality,” “basic activities of daily living,” “disability,” and scales that measure functional performance: “Disability Assessment for Dementia-DAD,” “Functional Activities Questionnaire (FAQ),” “Direct Assessment of Functional Status (DAFS).” To be included in the review, the study had to mention the characterization of the functional status of patients with bvFTD in the objectives of the study, using a previously validated instrument of functional assessment. Fourteen studies met this criterion. The reviewed studies suggested that individuals with bvFTD have greater functional impairment when compared to those with other subtypes of frontotemporal lobar degeneration or Alzheimer's disease. The studies documented a significant association between cognitive impairment and measures of functionality in these patients. The cognitive profile of patients may predict faster functional decline.

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Behavioral and activities of daily living inventories in the diagnosis of frontotemporal lobar degeneration and Alzheimer's disease

Cited by 9 publications

References 37 publications

Accuracy of neuropsychological tests and the Neuropsychiatric Inventory in differential diagnosis between Frontotemporal dementia and Alzheimer's disease

Accuracy of neuropsychological tests and the Neuropsychiatric Inventory in differential diagnosis between Frontotemporal dementia and Alzheimer's disease

Development, validity, and reliability of the General Activities of Daily Living Scale: a multidimensional measure of activities of daily living for older people

Functional Status in Behavioral Variant Frontotemporal Dementia: A Systematic Review

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