1983
DOI: 10.1093/rheumatology/22.3.134
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Bed Rest, Activity and the Inflammation of Rheumatoid Arthritis

Abstract: Seventy-five patients with rheumatoid arthritis have been studied in order to assess the relative contributions of bed rest and planned activity on the observed improvement in arthritis during hospitalization. The benefit of bed rest was less than expected; only a third of patients showed significant improvement. A similar number improved during planned activity and although bed rest was superior the advantages were small. The features of those patients who responded to bed rest or planned activity showed smal… Show more

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Cited by 45 publications
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“…For the individual, arthritis causes pain, activity limitations, and a lower quality of life. Traditionally, the cornerstone of treatment of active disease has been bed rest, and patients have been restrained from active physical exercise based on the presumption of its detrimental effect on disease activity and joint erosiveness (22).…”
Section: Discussionmentioning
confidence: 99%
“…For the individual, arthritis causes pain, activity limitations, and a lower quality of life. Traditionally, the cornerstone of treatment of active disease has been bed rest, and patients have been restrained from active physical exercise based on the presumption of its detrimental effect on disease activity and joint erosiveness (22).…”
Section: Discussionmentioning
confidence: 99%
“…Until the end of the 1970s, conventional RA treatment included rest combined with pharmacotherapy and physiotherapy centered on the reduction of specific motor disabilities. Rest did not bring as many benefits as expected, and it was found only marginally superior to activity in a large group of patients (5). Consequently, a growing interest began to emerge in global intervention directed at functional recovery, including cardiorespiratory training, muscle strengthening, and joint mobility.…”
Section: Introductionmentioning
confidence: 87%
“…Similar cautious regimens have previously been suggested for other rheumatic conditions, e.g. for rheumatoid arthritis (RA), where increased disease activity was assumed to follow exercise (16). During the last decades, however, exercise has proved to be safe and bene®cial in RA (17,18).…”
mentioning
confidence: 91%