Bazı süt ürünlerinde likit kromatografi/tandem kütle spektrometresi ile fitalat tayini

Abstract

This study was aimed to determine the presence and amount of the phthalates in yoghurt and ayran samples consumed in Turkey. For this purpose, 36 yoghurt and 24 ayran samples were used as materials in original packages collected from different markets in Turkey. The presence and the amounts of di-n-butyl phthalate (DBP), di (2-ethylhexyl) phthalate (DEHP), benzyl butyl phthalate (BBP), di-isononyl phthalate (DINP), di-n-octyl phthalate (DNOP) and diisodecyl phthalate (DIDP) were determined by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The results of the analysis howed that DBP, DEHP and BBP were present in the yoghurt samples whereas DINP, DIDP and DNOP were found to be lower than the detectable limit 20 µg/kg. The lowest and the highest mounts of DBP, DEHP and BBP in yoghurt samples are 6-229, 24-122, 22-63 µg/kg respectively. The lowest and highest phthalate amounts in ayran samples are determined to be 38-59 µg/kg for DBP and 26-81 µg/kg for DEHP. According to the results, although DEHP and DBP were the main phthalate esters in all milk products that were analyzed, the phthalate values of the samples were found to be less than the limit values (P<0.001).

Comprehensive Insight from Phthalates Occurrence: From Health Outcomes to Emerging Analytical Approaches

“…The study allowed the quantification of five PAEs, which exhibited the highest amounts for DnOP (1261.10 ng/L), while for DMP (2.66 ng/L), lower amounts were obtained. Korkmaz and collaborators [ 89 ] also analyzed milk products (36 yogurt and 24 ayran samples) for the presence of PAEs. The lowest and the highest amounts of DBP, DEHP, and BBP in yogurt samples were in the range of 6–229 µg/kg, 24–122 µg/kg, 22–63 µg/kg, respectively.…”

“…Table 2 summarizes the extraction techniques adopted in the last three years to analyze PAEs in environmental and food matrices. It is possible to observe that the most common extraction techniques used to extract phthalates from environmental and food samples are LLE [ 62 , 63 , 64 , 71 , 74 , 76 , 77 , 89 , 91 , 94 , 95 , 96 , 99 , 104 , 106 , 109 , 110 , 112 ], SPME [ 60 , 69 , 81 , 82 , 92 , 93 , 115 ], QuEChERS-dSPE [ 79 , 88 , 102 ], SPE [ 68 , 75 ], and soxhlet [ 100 , 101 , 114 ].…”

“…Although UV detectors have been demonstrated to be suitable for quantification of PAEs, they do not provide detailed structural information of known target compounds, being this its main drawback. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) [ 76 , 82 , 89 ] has been explored as an alternative to HPLC-UV, HPLC-DAD since it has shown higher sensitivity, selectivity, resolution, and effectiveness. Moreover, MS detectors are a potent instrument to identify and check molecular structures of unidentified compounds and qualitative analysis.…”

Evaluation of the Occurrence of Phthalates in Plastic Materials Used in Food Packaging

“…However, a higher LOD (from 0.12 to 0.50 µg/L) was achieved previously to quantify six phthalates in environmental waters using liquid-liquid extraction (LLE) followed by GC-MS [26]. A summary of the different analytical methods, used for phthalates determination in plastic packaging, is presented in Table 3 [20,21,24,[27][28][29][30][31][32][33][34][35][36].…”

“…Therefore, the results indicate that the proposed green extraction technique was effective and feasible for the determination of phthalates in plastic-based food packaging. Several studies (Table 5) revealed that phthalates and the ester derivative are passively ingested from the general environment, foods, drinks, breathing air, and dairy life products, causing various dysfunctions [3,20,30,31,34,[37][38][39][40][41][42][43][44][45][46]. Exposures to DEHP, BBP, DBP, and DEP are associated with dermatitis, conjunctivitis, and allergic symptoms [47].…”