Batch and Flow-Injection Spectrophotometric Determination of Thymol Using Procaine Hydrochloride as a New Chromogenic Reagent

Al-Ward, Hind S.; Al-Abachi, Mouyed Q.

doi:10.21123/bsj.9.2.302-310

Cited by 9 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…High-performance liquid chromatography (HPLC) [10], gas chromatography-mass spectrometry [11] and spectrophotometry [12] are conventional techniques to detect thymol. In comparison with these methods, the electrochemical method has attracted much attention due to its simple operation, low cost, fast detection, high sensitivity and good selectivity.…”

Section: Introductionmentioning

confidence: 99%

Design and Application of Thymol Electrochemical Sensor Based on the PtNPs-CPOFs-MWCNTs Composite

Zhang

Cui

et al. 2023

Molecules

View full text Add to dashboard Cite

In this study, the preparation of covalent polyoxometalate organic frameworks (CPOFs) is introduced using the idea of polyoxometalate and covalent organic frameworks. Firstly, the prepared polyoxometalate was functionalized with an amine group (NH2-POM-NH2), and then the CPOFs were prepared by a solvothermal Schiff base reaction with NH2-POM-NH2 and 2,4,6-trihydroxybenzene-1,3,5-tricarbaldehyde (Tp) as monomers. After the incorporation of PtNPs and MWCNTs into the CPOFs material, the PtNPs-CPOFs-MWCNTs nanocomposites, which possess excellent catalytic activity and electrical conductivity, were formed and utilized as new electrode materials for the electrochemical thymol sensors. The obtained PtNPs-CPOFs-MWCNTs composite exhibits excellent activity toward thymol, which is attributable to its large special surface area, good conductivity and the synergistic catalysis of each component. Under optimal experimental conditions, the sensor presented a good electrochemical response to thymol. The sensor shows two good linear relationships between the current and thymol concentration in the range of 2–65 μM (R2 = 0.996) and 65–810 μM (R2 = 0.997), with the corresponding sensitivity of 72.7 μA mM−1 and 30.5 μA mM−1, respectively. Additionally, the limit of detection (LOD) was calculated to be 0.2 μM (S/N = 3). At the same time, the prepared thymol electrochemical sensor revealed superior stability and selectivity. The constructed PtNPs-CPOFs-MWCNT electrochemical sensor is the first example of thymol detection.

show abstract

Section: Introductionmentioning

confidence: 99%

Design and Application of Thymol Electrochemical Sensor Based on the PtNPs-CPOFs-MWCNTs Composite

Zhang

Cui

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

“…Thymol is more investigated than carvacrol. Thymol determination is based on the diazotization-coupling reactions [ 7 , 8 , 9 , 10 ] or reactions with other reagents [ 11 ] with the following spectrophotometric detection. The determination of carvacrol in nanoemulsions is based on its absorption at 275 nm after recovery with acetonitrile [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Electrode Based on the MWCNTs and Electropolymerized Thymolphthalein for the Voltammetric Determination of Total Isopropylmethylphenols in Spices

Chernousova

Ziyatdinova

2023

Micromachines

View full text Add to dashboard Cite

Isopropylmethylphenols, namely thymol and carvacrol, are natural phenolic monoterpenoids with a wide spectrum of bioactivity making them applicable in the cosmetic, pharmaceutical, and food industry. The dose-dependent antioxidant properties of isopropylmethylphenols require their quantification in real samples. Glassy carbon electrode (GCE) modified with multi-walled carbon nanotubes (MWCNTs) and electropolymerized thymolphthalein has been developed for the sensitive quantification of isopropylmethylphenols. Conditions of thymolphthalein electropolymerization (monomer concentration, number of cycles, and electrolysis parameters) providing the best response to thymol have been found. Scanning electron microscopy and electrochemical methods confirm the effectivity of the electrode developed. The linear dynamic ranges of 0.050–25 and 25–100 µM for thymol and 0.10–10 and 10–100 µM for carvacrol with detection limits of 0.037 and 0.063 µM, respectively, have been achieved in differential pulse mode in Britton–Robinson buffer pH 2.0. The selectivity of the isopropylmethylphenols response in the presence of typical interferences (inorganic ions, saccharides, ascorbic acid) and other phenolics (caffeic, chlorogenic, gallic and rosmarinic acids, and quercetin) is a significant advantage over other electrochemical methods. The electrode has been used in the analysis of oregano and thyme spices. Total isopropylmethylphenols contents have been evaluated after a single sonication-assisted extraction with methanol.

show abstract

Voltammetric Determination of Thymol in Oregano Using CeO2-Modified Electrode in Brij® 35 Micellar Medium

et al. 2016

View full text Add to dashboard Cite

Batch and Flow-Injection Spectrophotometric Determination of Thymol Using Procaine Hydrochloride as a New Chromogenic Reagent

Cited by 9 publications

References 1 publication

Design and Application of Thymol Electrochemical Sensor Based on the PtNPs-CPOFs-MWCNTs Composite

Design and Application of Thymol Electrochemical Sensor Based on the PtNPs-CPOFs-MWCNTs Composite

Electrode Based on the MWCNTs and Electropolymerized Thymolphthalein for the Voltammetric Determination of Total Isopropylmethylphenols in Spices

Voltammetric Determination of Thymol in Oregano Using CeO2-Modified Electrode in Brij® 35 Micellar Medium

Contact Info

Product

Resources

About