Basketful Benefit of Citrus Limon

Dev, Chaturvedi; Suhane, Rishi Raj Nidhi Shrivastava

doi:10.7897/2230-8407.07653

Cited by 26 publications

(16 citation statements)

References 2 publications

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“…Lemon (Citrus limon) is one of the plants that is very useful for health and comes from Southeast Asia, with its tropical and subtropical climates. 1 One of the places for lemonade plantations in Indonesia is Batu City, East Java Province, located in an active volcanic area, such as Bromo, Tengger, and Semeru, which make land in this area fertile. Batu is located on a plateau, so it has low temperatures and high humidity.…”

Section: Introductionmentioning

confidence: 99%

“…These EOs contain bioactive compounds, such as limonene, up to 64%-90%, which are believed to have anti-inflammatory activity and low toxicity. 1,5,[7][8][9][10] According to the World Health Organization (WHO), plants are the best source for various types of drugs. The WHO estimates that around 3-4 billion people use herbal medicine and as many as 80% of individuals from developing countries use traditional medicines with basic ingredients from plants.…”

Section: Introductionmentioning

confidence: 99%

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Citrus limon Peel Essential Oil–Induced Type IV Hypersensitivity Reaction

Mahdani

Parmadiati

Ernawati

et al. 2020

JEP

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Background: Several studies have shown anti-inflammatory, anti-microbial, antifungal, and antioxidant effects from Citrus limon-peel essential oil (Cl-PEO). Cl-PEO can be developed as topical drugs for oral ulceration because of its potential active components. There have been no studies on the topical application of Cl-PEO inducing type IV hypersensitivity reaction. Purpose: To investigate the potential of Cl-PEO from Batu City to induce type IV hypersensitivity reactions based on clinical changes, lymphocytes, macrophages, IFNγ, andIL10 expression. Methods: This study was adapted from a guinea pig maximization-test method in Indonesia and the guidance of ISO 10,993-10:2010, and conducted on 20 guinea pigs (Cavia cobaya) divided into a control group and a treatment group. The treatment group was given Cl-PEO and the control group CMC-Na. Clinical changes were observed, then tissue specimens taken for hematoxylin-eosin and immunohistochemistry staining. Results: There were no clinical changes after exposure. Lymphocyte and macrophage numbers and IFNγ and IL10 expression increased in the treatment group compared to the control group (p=0). Conclusion: Cl-PEO can induce type IV hypersensitivity reactions in guinea pigs based on cellular and molecular cytokines, but there are no clinical changes after topical application.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Citrus limon Peel Essential Oil–Induced Type IV Hypersensitivity Reaction

Mahdani

Parmadiati

Ernawati

et al. 2020

JEP

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“…The results of research conducted by Shrivastava, et al (9) showed that Citrus limon could be used as a pediculicide, and Citrus limon juice without dilution or addition of distilled water could kill 95%5% P. h. capitis within 3 hours. The research results conducted by El Akkad, et al (12) showed that Citrus limon juice had a higher pediculicidal effect (100%) compared to olive oil (96.7%) and tea tree oil (23.3%).…”

Section: Allium Sativum Effectiveness Testmentioning

confidence: 99%

In Vitro Test on the Effectiveness of Citrus limon and Allium sativum as Pediculicides

Susanty

Lesmana

Afandi

et al. 2020

JKB

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Excessive usage of synthetic pediculicides, such as permethrin, lindane, and malathion, can induce resistance, environmental pollution, health problems, and even death. Efforts to prevent the side-effects of synthetic pediculicides are needed, one of which is by shifting to powerful yet safe natural pediculicides, such as Citrus limon (lemon) and Allium sativum (garlic). This study aimed to observe the effective concentration of Citrus limon and Allium sativum in vitro on the mortality of Pediculus humanus capitis (P. h. capitis). This research was an experimental laboratory study conducted in July to September 2019 in the Laboratory of Parasitology at Faculty of Medicine, University of Riau, while the making of Allium sativum extract was done at the Faculty of Mathematics and Science, University of Riau. A total of 288 samples of adult P. h. capitis was taken from children in two orphanages in Pekanbaru. Citrus limon juice and Allium sativum extract of 25%, 50%, 75%, and 100% concentrations, permethrin 1% as the positive control, and distilled water as the negative control were used in this study, and repetition was done three times. P. h. capitis mortality was observed every 10 - 120 minutes, characterized by the absence of movement of the legs and antenna. Data analysis was performed after 120 minutes with the one-way ANOVA test, LSD (=0.05), and Lethal Concentration 50 test (LC50). The one-way ANOVA test results of this study showed that statistically Citrus limon juice and Allium sativum extracts showed differences in each treatment formulation of juice on P. h. capitis mortality (Sig 0.017<0.05 and Sig 0.000<0.05) and LC50 juice of Citrus limon and Allium sativum extract by 51.999% and 72.426%. In this study, Citrus limon juice and Allium sativum extract had effect as pediculicides.

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“…C. papaya grown in various parts of the world, including India, tropical America and Europe. 17 Zuhrotun N et al, 18 points out that C. papaya extract have potential as anticancer through mechanism anti-proliferation and apoptosis induction. As Zuhrotun observes: 'mechanism of papaya leaf extract to inhibit the proliferation of breast cancer cells MCF-7 allegedly through the reduction of Reactive Oxygen Species (ROS) by antioxidant compounds contained in papaya leaf extract impact on the decrease of nuclear factor-κB (NF-κB) and impact on the gene expression associated with oxidative stress in MCF-7 cells such as COX-2, AP-1, Bcl-2 and Bcl-XL which can inhibit the proliferation of breast cancer cells MCF-7'.…”

Section: (Product B)mentioning

confidence: 99%

Health benefits of commercialized herbal product in Malaysia-a review

Zaini

Mustaffa

2019

PPIJ

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Recently, Malaysian herbal industry has emerged and commercialized herbal products are widely marketed as health boosters. The benefits of the product are one of the most significant current discussions among public and scientist. It is always a contradiction among public belief and scientific data about the pharmacological effect of herbal product. Hence, various researchers were anticipated to scientifically prove the medicinal claim of different herbal product. Thus, this review provides an important opportunity to advance the understanding of research and development of the marketed herbal products.

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Basketful Benefit of Citrus Limon

Cited by 26 publications

References 2 publications

<p><em>Citrus limon</em> Peel Essential Oil–Induced Type IV Hypersensitivity Reaction</p>

<p><em>Citrus limon</em> Peel Essential Oil–Induced Type IV Hypersensitivity Reaction</p>

In Vitro Test on the Effectiveness of Citrus limon and Allium sativum as Pediculicides

Health benefits of commercialized herbal product in Malaysia-a review

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