Basics of Skeletal Muscle Function and Normal Physiology

Brown, S.; Sewry, Caroline A.

doi:10.1016/b978-0-12-800040-3.00002-9

Cited by 5 publications

(3 citation statements)

References 73 publications

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“…For structural changes, this variable is understood as the area perpendicular to the muscle fibers compared to the total area of the muscle. In addition, its presence, in a greater quantity, is considered a predictor of greater strength, which is why it has a direct relationship with strength [30,31].…”

Section: Results Variablesmentioning

confidence: 99%

Effect of Blood Flow Restriction on Functional, Physiological and Structural Variables of Muscle in Patients with Chronic Pathologies: A Systematic Review

Reina-Ruiz

Galán-Mercant

Molina-Torres

et al. 2022

IJERPH

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The main objective of this systematic review of the current literature is to analyze the changes that blood flow restriction (BFR) causes in subjects with neuro-musculoskeletal and/or systemic pathologies focusing on the following variables: strength, physiological changes, structural changes and cardiocirculatory variables. The search was carried out in seven databases, including randomized clinical trials in which therapeutic exercise was combined with the blood flow restriction tool in populations with musculoskeletal pathologies. Outcome variables are strength, structural changes, physiological changes and cardiocirculatory variables. Twenty studies were included in the present study. Although there is a lot of heterogeneity between the interventions and evaluation instruments, we observed how the restriction of blood flow presents significant differences in the vast majority of the variables analyzed. In addition, we observed how BFR can become a supplement that provides benefits when performed with low intensity, similar to those obtained through high-intensity muscular efforts. The application of the BFR technique can provide benefits in the short and medium term to increase strength, muscle thickness and cardiovascular endurance, even improving the physiological level of the cardiovascular system. In addition, BFR combined with low-load exercises also achieves benefits comparable to high-intensity exercises without the application of BFR, benefiting patients who are unable to lift high loads.

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Section: Results Variablesmentioning

confidence: 99%

Effect of Blood Flow Restriction on Functional, Physiological and Structural Variables of Muscle in Patients with Chronic Pathologies: A Systematic Review

Reina-Ruiz

Galán-Mercant

Molina-Torres

et al. 2022

IJERPH

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“…• Dystrophin protein Dystrophin is an exceptionally large structural rod-shaped cytoskeletal protein that gives mechanical support to the sarcolemma (Figure 2) (Brown & Sewry, 2017). It plays a critical role in connecting the cytoskeleton of muscle fibers to the extracellular matrix.…”

Section: Dystrophin Utrophin and Calcium Regulatory Proteinsmentioning

confidence: 99%

“…Myofibers have a unique intracellular structure made up of different sarcolemmal proteins (like dystroglycan and sarcoglycan) and subsarcolemmal proteins (such as syntrophin and dystrobrevin) that enable muscle contraction (Brown & Sewry, 2017). The cytoskeleton and extracellular matrix are linked by the dystroglycan protein, which gives the myocyte structural support and stability.…”

Section: Muscle Morphology and Molecular Structurementioning

confidence: 99%

Duchenne and Becker muscular dystrophy: Cellular mechanisms, image analysis, and computational models: A review

Escobar‐Huertas,

Vaca‐González,

Guevara

et al. 2024

Cytoskeleton

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The muscle is the principal tissue that is capable to transform potential energy into kinetic energy. This process is due to the transformation of chemical energy into mechanical energy to enhance the movements and all the daily activities. However, muscular tissues can be affected by some pathologies associated with genetic alterations that affect the expression of proteins. As the muscle is a highly organized structure in which most of the signaling pathways and proteins are related to one another, pathologies may overlap. Duchenne muscular dystrophy (DMD) is one of the most severe muscle pathologies triggering degeneration and muscle necrosis. Several mathematical models have been developed to predict muscle response to different scenarios and pathologies. The aim of this review is to describe DMD and Becker muscular dystrophy in terms of cellular behavior and molecular disorders and to present an overview of the computational models implemented to understand muscle behavior with the aim of improving regenerative therapy.

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Biologics for Skeletal Muscle Healing: The Role of Senescence and Platelet-Based Treatment Modalities

Oberlohr

Lengel

Hambright

et al. 2020

Operative Techniques in Sports Medicine

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Basics of Skeletal Muscle Function and Normal Physiology

Cited by 5 publications

References 73 publications

Effect of Blood Flow Restriction on Functional, Physiological and Structural Variables of Muscle in Patients with Chronic Pathologies: A Systematic Review

Effect of Blood Flow Restriction on Functional, Physiological and Structural Variables of Muscle in Patients with Chronic Pathologies: A Systematic Review

Duchenne and Becker muscular dystrophy: Cellular mechanisms, image analysis, and computational models: A review

Biologics for Skeletal Muscle Healing: The Role of Senescence and Platelet-Based Treatment Modalities

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